JCI Insight

Title Publication Date Language Citations
ROR1-CAR T cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models2019/09/19English127
Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets2019/03/07English125
Human hepatic organoids for the analysis of human genetic diseases2017/09/07English125
Primary tumors induce neutrophil extracellular traps with targetable metastasis-promoting effects2019/08/22English124
Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus2018/04/19English123
Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer2020/06/18English121
Multiparametric immune profiling in HPV– oral squamous cell cancer2017/07/20English121
Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity2019/01/24English120
mTOR pathway activation drives lung cell senescence and emphysema2018/02/08English119
Differential decay of intact and defective proviral DNA in HIV-1–infected individuals on suppressive antiretroviral therapy2020/02/27English119
Zika virus productively infects primary human placenta-specific macrophages2016/08/18English119
Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome2016/12/22English118
CD226 opposes TIGIT to disrupt Tregs in melanoma2018/07/25English118
The evolving relationship of wound healing and tumor stroma2018/09/20English118
Human adipose beiging in response to cold and mirabegron2018/08/09English118
Extrapulmonary Aspergillus infection in patients with CARD9 deficiency2016/10/20English117
Randomized trial of intravenous iron-induced hypophosphatemia2018/12/06English116
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction2018/06/07English116
Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy2016/04/21English115
Neutrophil extracellular traps promote macrophage inflammation and impair atherosclerosis resolution in diabetic mice2020/04/09English115
Phase 2a randomized, placebo-controlled study of anti–IL-33 in peanut allergy2019/11/14English114
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles2018/06/21English113
Lack of immunoediting in murine pancreatic cancer reversed with neoantigen2016/09/08English113
PIK3CA-associated developmental disorders exhibit distinct classes of mutations with variable expression and tissue distribution2016/06/16English113
Eosinophilic esophagitis–linked calpain 14 is an IL-13–induced protease that mediates esophageal epithelial barrier impairment2016/04/07English113
T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response2017/04/20English113
Transplantation of human skin microbiota in models of atopic dermatitis2016/07/07English113
PD-1 blockade enhances the vaccination-induced immune response in glioma2016/07/07English112
Old age causes de novo intracortical bone remodeling and porosity in mice2017/09/07English112
A human-origin probiotic cocktail ameliorates aging-related leaky gut and inflammation via modulating the microbiota/taurine/tight junction axis2020/05/07English112