JCI Insight

Title Publication Date Language Citations
Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis2023/08/22English
Reverse electrical remodeling in rats with heart failure and preserved ejection fraction2023/07/10English
Stress-enhanced cardiac lncRNA Morrbid protects hearts from acute myocardial infarction2023/08/22English
Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition2023/08/22English
Positive and negative regulation of the Fcγ receptor–stimulating activity of RNA-containing immune complexes by RNase2023/08/22English
SRF deletion results in earlier disease onset in a mouse model of amyotrophic lateral sclerosis2023/08/08English
CD84 is a regulator of the immunosuppressive microenvironment in multiple myeloma2023/07/24English
T cell activation is insufficient to drive SIV disease progression2023/07/24English
Heterozygous mutations in SOX2 may cause idiopathic hypogonadotropic hypogonadism via dominant-negative mechanisms2023/02/08English
Murine cytomegalovirus reactivation concomitant with acute graft-versus-host disease is controlled by antibodies2023/03/08English
Gastric bypass alters diurnal feeding behavior and reprograms the hepatic clock to regulate endogenous glucose flux2023/03/22English
Hepatic HIF2 is a key determinant of manganese excess and polycythemia in SLC30A10 deficiency2024/04/23English
Fabry disease Schwann cells release p11 to induce sensory neuron hyperactivity2024/03/07English
Evaluating immunotherapeutic outcomes in triple-negative breast cancer with a cholesterol radiotracer in mice2024/03/19English
CETP inhibition enhances monocyte activation and bacterial clearance and reduces streptococcus pneumonia–associated mortality in mice2024/04/22English
Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial2024/03/14English
Characteristics and Determinants of Pulmonary Long COVID2024/04/23English
Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction2024/04/22English
In utero and postnatal ivacaftor/lumacaftor therapy rescues multiorgan disease in CFTR-F508del ferrets2024/04/22English
Myosin folding boosts solubility in cardiac muscle sarcomeres2024/03/14English
Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia2024/04/22English
P2Y13 receptor deficiency favors adipose tissue lipolysis and worsens insulin resistance and fatty liver disease2024/03/12English
MiRNA-148a-containing GMSC-derived EVs modulate Treg/Th17 balance via IKKB/NF-κB pathway and treat a rheumatoid arthritis model2024/04/23English
Intimomedial tears of the aorta heal by smooth muscle cell–mediated fibrosis without atherosclerosis2024/04/09English
Altered lipid homeostasis is associated with cerebellar neurodegeneration in SNX14 deficiency2024/04/16English
Molecular mechanism responsible for sex differences in electrical activity of mouse pancreatic β-cells2024/02/15English
Potentiating the radiation-induced type I interferon anti-tumoral immune response by ATM inhibition in pancreatic cancer2024/02/20English
Skeletal phenotype amelioration in mucopolysaccharidosis VI requires intervention at the earliest stages of postnatal development2023/11/08English
Inhibition of retinoic acid signaling in proximal tubular epithelial cells protects against acute kidney injury2023/10/23English
Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption2023/10/23English