Gene Therapy

Titel Veröffentlichungsdatum Sprache Zitate
Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo2003/11/17English307
Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid2006/08/17English299
Chemical modification and design of anti-miRNA oligonucleotides2011/07/14English296
Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery1999/04/01English289
Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle2002/03/01English286
MicroRNA therapeutics2011/04/28English282
Gene therapy progress and prospects: non-viral gene therapy by systemic delivery2006/09/01English279
Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial2012/06/21English273
Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers2004/07/22English269
Human mesenchymal stem cells: from basic biology to clinical applications2007/11/08English267
Progress and prospects: naked DNA gene transfer and therapy2003/03/01English264
Polyethylenimine-based intravenous delivery of transgenes to mouse lung1998/09/01English262
Electropermeabilization of skeletal muscle enhances gene transfer in vivo1999/04/01English261
A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium2006/04/20English259
Immune response to green fluorescent protein: implications for gene therapy1999/07/01English258
Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates2013/01/10English251
Gene therapy progress and prospects: Ultrasound for gene transfer2007/03/01English250
Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection1999/04/01English247
Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents2000/01/01English246
Intracellular trafficking of nonviral vectors2005/08/04English244
Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene2002/01/01English243
Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?2005/09/29English243
Characterization of cationic lipid-protamine–DNA (LPD) complexes for intravenous gene delivery1998/07/01English242
Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application2001/01/01English242
Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery1997/05/01English241
Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area2003/02/01English240
Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems2017/01/17English239
The silent treatment: siRNAs as small molecule drugs2006/01/05English238
Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?2001/01/01English237
Microbubble-enhanced ultrasound for vascular gene delivery2000/12/01English231