Melatonin: reducing the toxicity and increasing the efficacy of drugs

Article Properties
  • Language
    English
  • Publication Date
    2002/10/01
  • Indian UGC (journal)
  • Refrences
    216
  • Citations
    299
  • Russel J Reiter University of Texas Health Science Center, Department of Cellular and Structural Biology, MC 7762, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
  • Dun-xian Tan University of Texas Health Science Center, Department of Cellular and Structural Biology, MC 7762, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
  • Rosa M Sainz University of Texas Health Science Center, Department of Cellular and Structural Biology, MC 7762, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
  • Juan C Mayo University of Texas Health Science Center, Department of Cellular and Structural Biology, MC 7762, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
  • Silvia Lopez-Burillo University of Texas Health Science Center, Department of Cellular and Structural Biology, MC 7762, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
Abstract
Cite
Reiter, Russel J, et al. “Melatonin: Reducing the Toxicity and Increasing the Efficacy of Drugs”. Journal of Pharmacy and Pharmacology, vol. 54, no. 10, 2002, pp. 1299-21, https://doi.org/10.1211/002235702760345374.
Reiter, R. J., Tan, D.- xian, Sainz, R. M., Mayo, J. C., & Lopez-Burillo, S. (2002). Melatonin: reducing the toxicity and increasing the efficacy of drugs. Journal of Pharmacy and Pharmacology, 54(10), 1299-1321. https://doi.org/10.1211/002235702760345374
Reiter, Russel J, Dun-xian Tan, Rosa M Sainz, Juan C Mayo, and Silvia Lopez-Burillo. “Melatonin: Reducing the Toxicity and Increasing the Efficacy of Drugs”. Journal of Pharmacy and Pharmacology 54, no. 10 (2002): 1299-1321. https://doi.org/10.1211/002235702760345374.
1.
Reiter RJ, Tan D xian, Sainz RM, Mayo JC, Lopez-Burillo S. Melatonin: reducing the toxicity and increasing the efficacy of drugs. Journal of Pharmacy and Pharmacology. 2002;54(10):1299-321.
Refrences
Title Journal Journal Categories Citations Publication Date
Melatonin increases the activity of the oxidative phosphorylation enzymes and the production of ATP in rat brain and liver mitochondria 2002
Melatonin protects against gastric ulceration and increases the efficacy of ranitidine and omeprazole in reducing gastric damage Journal of Pineal Research
  • Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
  • Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
  • Science: Physiology
  • Science: Biology (General)
  • Science: Chemistry: Organic chemistry: Biochemistry
2002
Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs Journal of Pineal Research
  • Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
  • Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
  • Science: Physiology
  • Science: Biology (General)
  • Science: Chemistry: Organic chemistry: Biochemistry
2002
Role of prostaglandins, nitric oxide, sensory nerves and gastrin in acceleration of ulcer healing by melatonin and its precursor, L‐tryptophan

Journal of Pineal Research
  • Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
  • Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
  • Science: Physiology
  • Science: Biology (General)
  • Science: Chemistry: Organic chemistry: Biochemistry
47 2002
Melatonin protects against gentamicin-induced nephrotoxicity in rats Journal of Pineal Research
  • Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
  • Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
  • Science: Physiology
  • Science: Biology (General)
  • Science: Chemistry: Organic chemistry: Biochemistry
2002
Refrences Analysis
Category Category Repetition
Science: Biology (General)110
Science: Chemistry: Organic chemistry: Biochemistry92
Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry77
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology75
Science: Physiology61
Medicine: Medicine (General)44
Medicine: Therapeutics. Pharmacology16
Medicine: Public aspects of medicine: Toxicology. Poisons16
Medicine: Internal medicine: Specialties of internal medicine: Nutritional diseases. Deficiency diseases9
Science: Biology (General): Cytology8
Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens7
Medicine7
Science: Physics6
Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system4
Science: Biology (General): Genetics4
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the digestive system. Gastroenterology4
Medicine: Surgery4
Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy3
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology3
Medicine: Medicine (General): Medical technology2
Science: Science (General)2
Medicine: Internal medicine2
Medicine: Internal medicine: Special situations and conditions: Geriatrics2
Medicine: Pediatrics2
Medicine: Otorhinolaryngology2
Technology: Home economics: Nutrition. Foods and food supply2
Science: Chemistry: General. Including alchemy2
Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system: Psychiatry1
Medicine: Gynecology and obstetrics1
Medicine: Dermatology1
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the musculoskeletal system1
Agriculture1
Agriculture: Agriculture (General)1
Science: Chemistry: Analytical chemistry1
Science: Chemistry1
The category Science: Biology (General) 110 is the most frequently represented among the references in this article. It primarily includes studies from Journal of Pineal Research and Life Sciences. The chart below illustrates the number of referenced publications per year.
Refrences used by this article by year
Citations
Title Journal Journal Categories Citations Publication Date
Melatonin's chromatic magic: Examining its role in orchestrating pigment biosynthesis in horticultural crops Scientia Horticulturae
  • Science: Botany: Plant ecology
  • Agriculture: Plant culture
  • Agriculture
  • Agriculture: Agriculture (General)
2024
Effect of Melatonin on Herpesvirus Type 1 Replication

International Journal of Molecular Sciences
  • Science: Biology (General)
  • Science: Chemistry: General. Including alchemy
  • Science: Chemistry
2024
Melatonin Relieves Paclitaxel-Induced Neuropathic Pain by Regulating pNEK2-Dependent Epigenetic Pathways in DRG Neurons ACS Chemical Neuroscience
  • Science: Biology (General)
  • Medicine: Therapeutics. Pharmacology
  • Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
  • Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
2023
The role of melatonin in preventing amiodarone-induced rat liver damage

Canadian Journal of Physiology and Pharmacology
  • Medicine: Therapeutics. Pharmacology
  • Science: Physiology
  • Medicine: Public aspects of medicine: Toxicology. Poisons
2023
Melatonin and 5-fluorouracil combination chemotherapy: opportunities and efficacy in cancer therapy

Cell Communication and Signaling
  • Medicine
  • Science: Biology (General): Cytology
  • Science: Biology (General): Genetics
  • Science: Biology (General): Cytology
19 2023
Citations Analysis
Category Category Repetition
Science: Biology (General)128
Science: Chemistry: Organic chemistry: Biochemistry100
Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry83
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology80
Science: Physiology78
Medicine: Medicine (General)60
Medicine: Therapeutics. Pharmacology42
Medicine: Public aspects of medicine: Toxicology. Poisons39
Medicine25
Science: Biology (General): Cytology25
Science: Chemistry22
Science: Biology (General): Genetics20
Science: Chemistry: General. Including alchemy20
Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens14
Science: Chemistry: Organic chemistry8
Medicine: Internal medicine: Specialties of internal medicine: Nutritional diseases. Deficiency diseases7
Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system6
Science: Biology (General): Reproduction6
Science: Science (General)5
Agriculture: Animal culture5
Agriculture: Plant culture5
Technology: Chemical technology: Biotechnology5
Science: Microbiology4
Medicine: Dentistry4
Medicine: Dermatology4
Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy4
Medicine: Internal medicine4
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the digestive system. Gastroenterology4
Science: Chemistry: Analytical chemistry4
Medicine: Medicine (General): Medical technology3
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology3
Medicine: Surgery3
Science: Chemistry: Physical and theoretical chemistry3
Philosophy. Psychology. Religion: Psychology3
Science: Physics3
Science3
Science: Zoology3
Geography. Anthropology. Recreation: Environmental sciences3
Medicine: Internal medicine: Special situations and conditions: Geriatrics3
Medicine: Gynecology and obstetrics3
Medicine: Internal medicine: Special situations and conditions3
Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid3
Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine2
Medicine: Pathology2
Agriculture: Animal culture: Veterinary medicine2
Technology: Chemical technology: Food processing and manufacture2
Technology: Home economics: Nutrition. Foods and food supply2
Agriculture2
Agriculture: Agriculture (General)2
Science: Botany: Plant ecology2
Technology: Environmental technology. Sanitary engineering2
Science: Biology (General): Ecology2
Medicine: Public aspects of medicine2
Medicine: Nursing2
Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system: Psychiatry2
Technology: Electrical engineering. Electronics. Nuclear engineering: Nuclear engineering. Atomic power1
Medicine: Pediatrics1
Medicine: Internal medicine: Special situations and conditions: Industrial medicine. Industrial hygiene1
Agriculture: Aquaculture. Fisheries. Angling1
Geography. Anthropology. Recreation: Oceanography1
Medicine: Internal medicine: Infectious and parasitic diseases1
Technology: Hydraulic engineering: River, lake, and water-supply engineering (General)1
Medicine: Otorhinolaryngology1
Medicine: Surgery: Anesthesiology1
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system1
Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system1
Technology1
The category Science: Biology (General) 128 is the most commonly referenced area in studies that cite this article. The first research to cite this article was titled Melatonin prevents methotrexate‐induced hepatorenal oxidative injury in rats and was published in 2003. The most recent citation comes from a 2024 study titled Effect of Melatonin on Herpesvirus Type 1 Replication. This article reached its peak citation in 2021, with 18 citations. It has been cited in 175 different journals, 21% of which are open access. Among related journals, the Journal of Pineal Research cited this research the most, with 70 citations. The chart below illustrates the annual citation trends for this article.
Citations used this article by year