Nature Methods

Title Publication Date Language Citations
Iterative correction of Hi-C data reveals hallmarks of chromosome organization2012/09/02English803
Cas9 as a versatile tool for engineering biology2013/09/27English801
Mechanical regulation of cell function with geometrically modulated elastomeric substrates2010/08/01English798
Accurate detection of complex structural variations using single-molecule sequencing2018/04/30English795
Ultramicroscopy: three-dimensional visualization of neuronal networks in the whole mouse brain2007/03/25English794
Identification of microRNAs of the herpesvirus family2005/02/16English793
A microfluidic culture platform for CNS axonal injury, regeneration and transport2005/07/21English789
Coding of facial expressions of pain in the laboratory mouse2010/05/09English788
MSFragger: ultrafast and comprehensive peptide identification in mass spectrometry–based proteomics2017/04/10English787
Highly inclined thin illumination enables clear single-molecule imaging in cells2008/01/06English783
CRISPR RNA–guided activation of endogenous human genes2013/07/25English778
Whole-brain functional imaging at cellular resolution using light-sheet microscopy2013/03/18English777
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research2017/02/28English774
Directed evolution of APEX2 for electron microscopy and proximity labeling2014/11/24English773
A practical guide to photoacoustic tomography in the life sciences2016/07/28English768
Bayesian approach to single-cell differential expression analysis2014/05/18English767
Rapid blue-light–mediated induction of protein interactions in living cells2010/10/31English767
Quantitative single-cell RNA-seq with unique molecular identifiers2013/12/22English755
A complete bacterial genome assembled de novo using only nanopore sequencing data2015/06/15English753
A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum2013/03/24English751
Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)2016/03/28English750
Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination2011/03/04English745
Target-enrichment strategies for next-generation sequencing2010/01/28English742
Detection and localization of single molecular recognition events using atomic force microscopy2006/04/20English742
Accurate determination of microbial diversity from 454 pyrosequencing data2009/08/09English730
CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo2015/08/31English730
MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics2011/10/02English727
Deep generative modeling for single-cell transcriptomics2018/11/30English725
FaST linear mixed models for genome-wide association studies2011/09/04English723
Caged compounds: photorelease technology for control of cellular chemistry and physiology2007/07/30English709