JCI Insight

Title Publication Date Language Citations
Anti–spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection2019/02/21English572
Diabetic retinopathy: current understanding, mechanisms, and treatment strategies2017/07/20English571
The head and neck cancer immune landscape and its immunotherapeutic implications2016/10/20English488
Generation and testing of clinical-grade exosomes for pancreatic cancer2018/04/19English480
Neutrophil extracellular traps in COVID-192020/04/24English478
Inhibition of neuronal ferroptosis protects hemorrhagic brain2017/04/06English434
Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation2018/01/11English347
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis2016/12/08English347
COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status2020/07/23English338
The laboratory tests and host immunity of COVID-19 patients with different severity of illness2020/05/21English333
Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity2020/05/07English330
Institutional implementation of clinical tumor profiling on an unselected cancer population2016/11/17English310
PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers2019/03/21English309
Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer’s disease2017/08/17English306
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype2016/02/25English301
Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury2018/02/08English290
Vaccine-generated lung tissue–resident memory T cells provide heterosubtypic protection to influenza infection2016/07/07English260
Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease2020/07/09English257
Necroptosis: a crucial pathogenic mediator of human disease2019/08/08English253
Brain-wide glymphatic enhancement and clearance in humans assessed with MRI2018/07/12English249
Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells2017/02/23English241
The complement system in COVID-19: friend and foe?2020/08/06English241
Semaglutide lowers body weight in rodents via distributed neural pathways2020/03/26English233
Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection2019/10/17English231
Interleukin-7 restores lymphocytes in septic shock: the IRIS-7 randomized clinical trial2018/03/08English230
An immune-based biomarker signature is associated with mortality in COVID-19 patients2021/01/11English226
Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma2017/06/15English222
CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer2017/06/02English218
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections2020/09/03English216
Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice2017/04/06English214