Xenobiotica

Title Publication Date Language Citations
Effect of diet on the urinary excretion of hippuric acid and other dietary-derived aromatics in rat. A complex interaction between diet, gut microflora and substrate specificity1998/01/01English153
Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man2002/01/01English151
Pharmacokinetic interactions between herbal remedies and medicinal drugs2002/01/01English149
Predicting drug clearance from recombinantly expressed CYPs: intersystem extrapolation factors2004/02/01English146
Cytochrome P450 forms in fish: Catalytic, immunological and sequence similarities1989/01/01English143
The metabolism of cypermethrin in man: differences in urinary metabolite profiles following oral and dermal administration1992/01/01English138
Drug Metabolism under Pathological and Abnormal Physiological States in Animals and Man1977/01/01English136
In vitrobiotransformation of flavonoids by rat liver microsomes1998/01/01English135
Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B12010/01/27English132
A regulatory viewpoint on transporter-based drug interactions2008/08/01English129
Biotransformation of diclofenac sodium (Voltaren®) in animals and in man1979/01/01English128
Disposition in male volunteers of a subanaesthetic intravenous dose of an oil in water emulsion of14C-propofol1988/01/01English128
The Metabolism of Tamoxifen (I.C.I. 46,474) Part I : In Laboratory Animals1973/01/01English127
Phase I and II enzyme characterization of two sources of HepG2 cell lines2004/03/01English126
Purification and characterization of microsomal cytochrome P-450s1982/01/01English125
Detoxication reactions of glutathione and glutathione transferases1986/01/01English123
Interaction of Cimetidine with Liver Microsomes1979/01/01English122
The iron-binding and hydroxyl radical scavenging action of anti-inflammatory drugs1988/01/01English121
Influence of a series of natural flavonoids on free radical generating systems and oxidative stress1994/01/01English121
Binding of14C-Carbon Tetrachloride to Microsomal Proteinsin vitroand Formation of CHCl3by Reduced Liver Microsomes1973/01/01English119
The metabolism of14C-oxcarbazepine in man1986/01/01English116
Mutagenic properties of allylic and α,β-unsaturated compounds: Consideration of alkylating mechanisms1982/01/01English116
Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, andin vitro–in vivocorrelations2007/11/01English116
Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin2001/01/01English116
Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics2013/07/05English115
Excretion and metabolism of di(2-ethylhexyl)-phthalate in man1985/01/01English113
Specific Carcinogenic and Teratogenic Effects of ‘Indirect’ Alkylating Methyl and Ethyl compounds, and their Dependency on Stages of Ontogenic Developments1973/01/01English112
Cytochrome P-450 and oxidative metabolism in molluscs1989/01/01English112
Measurement of oxybutynin and its N-desethyl metabolite in plasma, and its application to pharmacokinetic studies in young, elderly and frail elderly volunteers1992/01/01English112
Optimization of Cryopreservation Procedures for Rat and Human Hepatocytes1989/01/01English109