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Xenobiotica
Title
Publication Date
Language
Citations
CYP-catalysed cycling of clozapine and clozapine- N -oxide promotes the generation of reactive oxygen species in vitro
2023/12/22
English
Novel application of PBBM to justify impact of faster dissolution on safety and pharmacokinetics – a case study and utility in regulatory justifications
2023/11/02
English
Effect of tubeimoside I on the activity of cytochrome P450 enzymes in human liver microsomes
2024/01/12
English
Indirubin mediates adverse intestinal reactions in guinea pigs by downregulating the expression of AchE through AhR
2024/01/08
English
Chronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver
2023/11/02
English
Population pharmacokinetics of mycophenolic acid and dose optimisation in adult Chinese kidney transplant recipients
2023/11/02
English
Comparative study on ABCB1-dependent efflux of anthracyclines and their metabolites: consequences for cancer resistance
2023/07/03
English
Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css–MRTpo method and chimeric mice with humanised livers
2023/09/02
English
Metabolite profiling and identification of enzymes responsible for the metabolism of hirsutine, a major alkaloid from Uncaria rhynchophylla
2023/07/03
English
Thank you to reviewers
2024/01/02
English
Preclinical pharmacokinetic investigation of the bioavailability and skin distribution of HY-072808 ointment, a novel drug candidate for the treatment of atopic dermatitis, in minipigs by a newly LC-MS/MS method
2024/03/15
English
Effects of pharmacogenetics on pharmacokinetics and toxicity of doxorubicin in Egyptian breast cancer patients
2024/03/15
English
Exploring the pharmacokinetics of second-generation cephalosporin, cefaclor: a systematic review in healthy and diseased populations
2024/04/02
English
The metabolism of the orexin-1 selective receptor antagonist nivasorexant
2024/03/01
English
Toxicokinetic and mass balance of morpholine in rats
2023/05/04
English
Meeting report: DMDG peptide and oligonucleotide ADME workshop 2022
2023/04/03
English
Characterisation of UDP-glucuronosyltransferase activity in sea turtle Chelonia mydas
2022/12/02
English
Selection of a Suitable Animal Model to Evaluate Secretion of Drugs in the Human Milk: A Systematic Approach
2024/04/18
English
Preparation, characterisation, pharmacokinetics and distribution of esculin microspheres administered via intravitreal injection into rabbit brain
2024/04/19
English
Developmental stage and infection status may affect drug distribution in the prostate of rats
2024/04/25
English
Monomethyl Auristatin E (MMAE), a Payload for Multiple Antibody Drug Conjugates (ADCs), Demonstrates Differential Red Blood Cell Partitioning Across Human and Animal Species
2024/04/22
English
mRNA expression levels of cytochrome P450 CYP1A2 , CYP3A4 , and CYP3A5 in the epidermis: a focus on individual differences among Japanese individuals
2024/04/24
English
Exploring precision-cut liver slices for comparative xenobiotic metabolism profiling in swine and cattle
2024/04/25
English
Young scientists meet at Pfizer
1999/01/01
English
Investigation of the potential interaction between terfenadine and tedisamil in human liver microsomes
1998/01/01
English
Species differences in β-oxidative metabolism of a thromboxane A 2 -receptor antagonist [(+)-S-145] in rat, dog and monkey
2001/03/01
Pharmacodynamic analysis between plasma level and inhibition of acid output after administration of a new histamine H2-receptor antagonist (Z-300) in dog
2000/01/01
English
Announcement
1997/01/01
English
Announcements
1997/01/01
English
Disposition of diphenyl sulphoxide in rat
1998/01/01
English
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