Title	Publication Date	Language	Citations
Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man	2008/06/01	English	48
Automated high throughput human CYP isoform activity assay using SPE-LC/MS method: application in CYP inhibition evaluation	2000/01/01	English	48
Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel	2009/10/21	English	48
Cynomolgus monkey CYPs: a comparison with human CYPs	2009/07/21	English	48
Metabolites of sodium selenite and methylated selenium compounds administered at cancer chemoprevention levels in the rat	1993/01/01	English	48
Species differences in blood profiles, metabolism and excretion of14C-propofol after intravenous dosing to rat, dog and rabbit	1991/01/01	English	48
On the metabolism of haloperidol	1993/01/01	English	48
Ethnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers	2005/01/01	English	48
Selectivity for inhibition of nilotinib on the catalytic activity of human UDP-glucuronosyltransferases	2013/09/25	English	48
Disposition and metabolism of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in the rat	1983/01/01	English	47
Enantioselective binding of Casodex to the androgen receptor	1996/01/01	English	47
Metabolismin vivoof 3,4,3′,4′-tetrachlorobiphenyl and toxicological assessment of the metabolites in rats	1987/01/01	English	47
Biological fate of sulphur mustard, 1,1′-thiobis(2-chloroethane): identification of β-lyase metabolites and hydrolysis products in human urine	1995/01/01	English	47
A phase I, open-label, single-dose, mass balance study of 14C-labeled abiraterone acetate in healthy male subjects	2012/09/28	English	47
Inhibition of drug metabolism in human liver microsomes by nizatidine, cimetidine and omeprazole	2001/01/01	English	47
Biological fate of sulphur mustard: identification of valine and histidine adducts in haemoglobin from casualties of sulphur mustard poisoning	1997/01/01	English	47
Utility of the carboxylesterase inhibitorbis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor	2010/03/18	English	47
Sources of interindividual variability in IVIVE of clearance: an investigation into the prediction of benzodiazepine clearance using a mechanistic population-based pharmacokinetic model	2011/03/24	English	47
Inhibition of zaleplon metabolism by cimetidine in the human liver:in vitrostudies with subcellular fractions and precision-cut liver slices	2002/01/01	English	47
Association of CYP3A4*18B polymorphisms with the pharmacokinetics of cyclosporine in healthy subjects	2007/03/01	English	47
Cytochrome P450 probe substrate metabolism kinetics in Sprague Dawley rats	2007/05/01	English	47
Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans	2007/04/01	English	47
Comparative pharmacokinetics and metabolism of levetiracetam, a new anti-epileptic agent, in mouse, rat, rabbit and dog	2004/03/01	English	47
Prediction of whole-body metabolic clearance of drugs through the combined use of slices from rat liver, lung, kidney, small intestine and colon	2004/03/01	English	46
Disposition and pharmacokinetics of temozolomide in rat	2004/05/01	English	46
Metabolism of quercetin and kaempferol by rat hepatocytes and the identification of flavonoid glycosides in human plasma	2002/01/01	English	46
Effect of phenethyl isothiocyanate on microsomalN-nitrosodimethylamine metabolism and other monooxygenase activities	1990/01/01	English	46
Time course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients and in HepaRG cells	2015/04/14	English	46
Metabolism, excretion and pharmacokinetics of [14C]crizotinib following oral administration to healthy subjects	2014/07/18	English	46
Reversible and irreversible inhibition of CYP3A enzymes by tamoxifen and metabolites	2002/01/01	English	46