Xenobiotica

Title Publication Date Language Citations
Ethnic-related differences in the frequency distribution of genetic polymorphisms in the CYP1A1 and CYP1B1 genes in Japanese and Caucasian populations2000/01/01English46
Triclabendazole biotransformation and comparative diffusion of the parent drug and its oxidized metabolites intoFasciola hepatica2004/01/01English46
The Metabolism of Terbutaline in Man1972/01/01English46
Inhibition of microsomal lipid peroxidation by α-tocopherol and α-tocopherol acetate1991/01/01English46
The Fate of Metronidazole and its Implications in Chemotherapy1975/01/01English46
Sulphoxidation of albendazole by the FAD-containing and cytochrome P-450 dependent mono-oxygenases from pig liver microsomes1987/01/01English46
Lindane-Induced Oxidative Stress. I. Time Course of Changes in Hepatic Microsomal Parameters, Antioxidant Enzymes, Lipid Peroxidative Indices and Morphological Characteristics1988/01/01English46
The Oxidative Metabolism of α-Chlorohydrin in the Male Rat and the Formation of Spermatocoeles1978/01/01English46
Cholesterol and non-cholesterol sterol transporters: ABCG5, ABCG8 and NPC1L1: a review2008/08/01English46
In vitrometabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P4502011/07/05English46
Species differences in hepatic and intestinal metabolic activities for 43 human cytochrome P450 substrates between humans and rats or dogs2013/04/17English46
CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavirin vitro2002/01/01English46
Effect of voriconazole and other azole antifungal agents on CYP3A activity and metabolism of tacrolimus in human liver microsomes2011/11/22English45
Studies Related to the Metabolism of Anabolic Steroids in the Horse: 19-Nortestosterone1977/01/01English45
Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily1999/01/01English45
Kinetic analysis of bile acid sulfation by stably expressed human sulfotransferase 2A1 (SULT2A1)2010/01/26English45
PEGylation of somatropin (recombinant human growth hormone): Impact on its clearance in humans2008/10/01English45
In vitrostability and metabolism of salvinorin A in rat plasma2009/04/07English45
Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: Analysis of interspecies variability and comparison with metabolismin vivo1994/01/01English45
Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily1998/01/01English45
Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derivedin vitrosystems2001/01/01English45
Metabolism of digoxin and digoxigenin digitoxosides in rat liver microsomes: involvement of cytochrome P4503A1999/01/01English45
Metabolism and disposition of 2,2′,4,4′- tetrabromodiphenyl ether following administration of single or multiple doses to rats and mice2006/01/01English45
The microbial metabolism of condensed (+)-catechins by rat-caecal microflora1986/01/01English45
The effect of hypolipidaemic agents on peroxisomal β-oxidation and mixed-function oxidase activities in primary cultures of rat hepatocytes. Relationship between induction of palmitoyl-CoA oxidation and lauric acid hydroxylation1984/01/01English45
Identification of 1-hydroxypyrene as a major metabolite of pyrene in pig urine1983/01/01English45
Biotransformation of ketamine, (Z)-6-hydroxyketamine, and (E)-6-hydroxyketamine by rat, rabbit, and human liver microsomal preparations1987/01/01English45
Debrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol1986/01/01English45
Variations in demethylation of N-methylnaltrexone in mice, rats, dogs, and humans1989/01/01English45
The Oxidative Metabolism of 1-Bromopropane in the Rat1979/01/01English45