Title	Publication Date	Language	Citations
Toward an improved prediction of humanin vivobrain penetration	2008/11/21	English	67
Cytochrome P-450 as a determinant of sex difference of drug metabolism in the rat	1982/01/01	English	67
Comparative enantioselectivity in the sulphoxidation of albendazole in man, dogs and rats	1991/01/01	English	67
Practical use of the regression offset approach for the prediction ofin vivointrinsic clearance from hepatocytes	2012/04/18	English	67
Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50shift approach facilitateskinactassay design	2009/02/01	English	67
Challenges and opportunities with modelling and simulation in drug discovery and drug development	2007/11/01	English	67
The SLC16 monocaboxylate transporter family	2008/08/01	English	66
Nuclear receptors CAR and PXR in the regulation of hepatic metabolism	2006/01/01	English	66
Pharmacogenetics of dextromethorphan O-demethylation in man	1986/01/01	English	66
Toxicity monitored with a correlated set of cell-culture assays	1985/01/01	English	65
The metabolism and excretion of (+)-[14C]cyanidanol-3 in man following oral administration	1983/01/01	English	65
Metabolism of Alkenebenzene Derivatives in the Rat. II. Eugenol and Isoeugenol Methyl Ethers	1976/01/01	English	65
Bile and Urine as Complementary Pathways for the Excretion of Foreign Organic Compounds	1976/01/01	English	65
Effects of diammonium glycyrrhizinate on the pharmacokinetics of aconitine in rats and the potential mechanism	2009/10/01	English	65
Kinetic determinants of hepatic clearance: Plasma protein binding and hepatic uptake	2007/11/01	English	65
Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of Mitragyna speciosa (kratom)	2019/01/07	English	65
Biotransformation of chlorpyrifos and diazinon by human liver microsomes and recombinant human cytochrome P450s (CYP)	2004/10/01	English	65
Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N -demethylation in human liver microsomes	2003/08/01	English	65
Human cytochrome P450s: selectivity and measurement in vivo	1998/01/01	English	65
Case report of extensive metabolism by aldehyde oxidase in humans: Pharmacokinetics and metabolite profile of FK3453 in rats, dogs, and humans	2011/03/09	English	64
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase	2002/01/01	English	64
Effect of Polycyclic Aromatic Hydrocarbons on Hepatic Microsomal Enzymes and Disposition of Methylnaphthalene in Rainbow Troutin vivo	1978/01/01	English	64
Bioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer	2012/11/16	English	64
Prediction ofin vivodrug clearance fromin vitrodata. II: Potential inter-ethnic differences	2006/06/01	English	64
Attenuating pregnane X receptor (PXR) activation: A molecular modelling approach	2007/02/01	English	64
Differential effect of genetic variants of Na+-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors	2010/10/15	English	63
Metabolism and disposition of 2,2′,4,4′,5-pentabromodiphenyl ether (BDE99) following a single or repeated administration to rats or mice	2006/06/01	English	63
Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III	2015/09/18	English	63
The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease	2013/11/06	English	63
Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion	1991/01/01	English	62