Title	Publication Date	Language	Citations
'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data	1999/01/01	English	2,739
Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic Compounds	1973/01/01	English	574
Interaction of a series of nitriles with the alcohol-inducible isoform of P450: Computer analysis of structure—activity relationships	1994/01/01	English	422
Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition	2008/08/01	English	374
Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid	1992/01/01	English	334
Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man	1999/01/01	English	311
Accumulation of metformin by tissues of the normal and diabetic mouse	1994/01/01	English	306
Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family	2008/08/01	English	296
Role of transport proteins in drug absorption, distribution and excretion	2001/01/01	English	278
Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells	2002/01/01	English	274
Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man	2000/01/01	English	271
Inhibition and induction of human cytochrome P450 (CYP) enzymes	1998/01/01	English	236
The Metabolism and Excretion of Curcumin (1,7-Bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the Rat	1978/01/01	English	224
Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9	1995/01/01	English	207
Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons	1995/01/01	English	203
Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition	2006/01/01	English	195
Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation ofin vitrometabolism using cDNA-expressed human P450s and human liver microsomes	1996/01/01	English	193
Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymes	1982/01/01	English	191
Intestinal permeability and its relevance for absorption and elimination	2007/11/01	English	189
Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes	2009/01/01	English	189
Interspecies scaling: predicting clearance of drugs in humans. Three different approaches	1996/01/01	English	178
Prediction ofin vivodrug clearance fromin vitrodata. I: Impact of inter-individual variability	2006/06/01	English	174
Determination of metabolites of xenobiotics in the bile of fish from polluted waterways	1984/01/01	English	169
Folate, folic acid and 5-methyltetrahydrofolate are not the same thing	2014/02/04	English	168
The Metabolism of Ibuprofen	1973/01/01	English	165
Cytochromes P-450 in rats: structures, functions, properties and relevant human forms	1992/01/01	English	162
Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues	2011/10/13	English	159
Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins	2008/08/01	English	157
Peptide transporters and their roles in physiological processes and drug disposition	2008/08/01	English	156
In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus	2000/01/01	English	153