Perspectives in Drug Discovery and Design

Titel Veröffentlichungsdatum Sprache Zitate
Synthetic combinatorial libraries: Views on techniques and their application1995/04/01English
Soluble analogs of GalCer and suramin as potential inhibitors of HIV-1 infection: Key role of self-association1996/12/01English
Suramin: A polysulfonated compound that inhibits the binding of HIV-1 gp120 to GalCer/sulfatide and blocks the CD4-independent pathway of HIV-1 infection in mucosal epithelial cells1996/12/01English
Substrate-based inhibitors of HIV-1 protease1993/08/01English
Antisense oligodeoxynucleotides: Internalization, compartmentalization and non-sequence specificity1996/12/01English
The role of the envelope glycoproteins in HIV-1 transmission and pathogenesis1996/12/01English
Possible role of nonprotein components of the plasma membrane in CD4-dependent membrane fusion and HIV entry1996/12/01English
HIV-permissive cells from solid tissues: Cytokine induction and effects1996/12/01English
PNP inhibitors1994/08/01English
Backward binding and other structural surprises1995/12/01English
Aspartic proteinases: The structures and functions of a versatile superfamily of enzymes1995/07/01English
The integrin αIIbβ3 as an antithrombotic target1994/04/01English
The medicinal chemistry of FK-5061994/08/01English
Crystal structures of thrombin and thrombin complexes as a framework for antithrombotic drug design1994/04/01English
MyristolyCoA:protein N-myristoyltransferase as a therapeutic target for inhibiting replication of human immunodeficiency virus-11993/08/01English
NMR for structural studies in drug discovery1995/12/01English
Cyclosporin A and FK-506: Immunosuppression, inhibition of transcription and the role of calcineurin1994/08/01English
Genetic determinants controlling HIV-1 tropism for CD4−/GalCer+ human intestinal epithelial cells1996/12/01English
Interactions of the human immunodeficiency virus with astrocytes1996/12/01English
HIV-1 infection of a CD4-negative primary cell type: The oligodendrocyte1996/12/01English
Immunosuppression1994/08/01English
Modern NMR spectroscopy of proteins and peptides in solution and its relevance to drug design1993/12/01English
Immunosuppression and the CD28 receptor1994/08/01English
Yeast as model T cells1994/08/01English
Clinical use of immunosuppressants in transplantation1994/08/01English
Preface1995/12/01English
The debate on the presence of HIV-1 virus in human spermatozoa1996/12/01English
Preface1996/12/01English
V3 loop-derived multibranched peptides as inhibitors of HIV infection in CD4+ and CD4− cells1996/12/01English
Proteolytic maturation of transforming growth factor-α1995/07/01English