Perspectives in Drug Discovery and Design

Titel Veröffentlichungsdatum Sprache Zitate
Host andPorphyromonas gingivalis proteinases in periodontitis: A biochemical model of infection and tissue destruction1995/07/01English
Pharmacology of CsA and FK-5061994/08/01English
Detection of functional galactosylceramide (GalCer) receptors on CD4-negative HIV-1 target cells1996/12/01English
Ticlopidine and clopidogrel: Antithrombotic agents that block ADP-mediated platelet activation1994/04/01English
HIV protease: Structure-based design1993/08/01English
Peptide nucleic acid (PNA): A lead for gene therapeutic drugs1996/12/01English
Factor Xa inhibitors1994/04/01English
Design and structure of symmetry-based inhibitors of HIV-1 protease1993/08/01English
HIV entry into cells by CD4-independent mechanisms1996/12/01English
Applications of free energy derivatives to analog design1995/12/01English
Morphological alterations associated with HIV infection of CD4−/GalCer+ human intestinal epithelial cells1996/12/01English
Interaction of human immunodeficiency virus type 1 envelope protein with liposomes containing galactosylceramide1996/12/01English
The metabolism of the amyloid precursor protein and its relevance to Alzheimer's disease1995/07/01English
Why are binding-site models more complicated than molecules?1993/12/01English
Design of antithrombotic agents: An introduction1994/04/01English
Galactosylceramide and transmembrane signalling in enterocytes: Calcium response induced by HIV-1 surface-envelope glycoprotein gp1201996/12/01English
Intravaginal formulations to prevent HIV infection1996/12/01English
Clinical use of immunosuppressants in autoimmune diseases1994/08/01English
HIV life cycle and genetic approaches1993/08/01English
Small synthetic inhibitors of cysteine proteases1996/12/01English
Recent insights into cysteine protease specificity: Lessons for drug design1996/12/01English
Cysteine proteinases in arthritis and inflammation1996/12/01English
Challenges and prospects for computational aids to molecular diversity1996/12/01English
Computer representation and manipulation of combinatorial libraries1996/12/01English
Commercial software systems for diversity analysis1996/12/01English
Cluster-based selection1996/12/01English
Descriptors for diversity analysis1996/12/01English
Computational tools for the analysis of molecular diversity1996/12/01English
Partition-based selection1996/12/01English
Developing an in-house system to support combinatorial chemistry1996/12/01English