Nature Methods

Title Publication Date Language Citations
Improving FRET dynamic range with bright green and red fluorescent proteins2012/09/09English511
High-definition spatial transcriptomics for in situ tissue profiling2019/09/09English511
Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase2005/01/21English510
Network-based stratification of tumor mutations2013/09/15English509
Pooled CRISPR screening with single-cell transcriptome readout2017/01/18English508
Large-scale de novo DNA synthesis: technologies and applications2014/04/29English501
Flow-enhanced vascularization and maturation of kidney organoids in vitro2019/02/11English500
Objective comparison of particle tracking methods2014/01/19English499
Content-aware image restoration: pushing the limits of fluorescence microscopy2018/11/26English499
Subunit counting in membrane-bound proteins2007/03/18English499
Addressing preferred specimen orientation in single-particle cryo-EM through tilting2017/07/03English498
Quantitative assessment of single-cell RNA-sequencing methods2013/10/20English497
Efficient multivariate linear mixed model algorithms for genome-wide association studies2014/02/16English496
Super-resolution video microscopy of live cells by structured illumination2009/04/26English495
Precise and reliable gene expression via standard transcription and translation initiation elements2013/03/10English493
Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro2015/12/21English491
SAINT: probabilistic scoring of affinity purification–mass spectrometry data2010/12/05English491
Proteogenomics: concepts, applications and computational strategies2014/10/30English491
Engineering of human brain organoids with a functional vascular-like system2019/10/07English490
G&T-seq: parallel sequencing of single-cell genomes and transcriptomes2015/04/27English490
Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins2011/12/18English488
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)2009/07/20English488
Measuring image resolution in optical nanoscopy2013/04/28English485
Comprehensive comparative analysis of strand-specific RNA sequencing methods2010/08/15English484
Nonblinking and long-lasting single-molecule fluorescence imaging2006/10/01English481
In situ sequencing for RNA analysis in preserved tissue and cells2013/07/14English480
Fiber-optic fluorescence imaging2005/11/18English479
Two-photon absorption properties of fluorescent proteins2011/04/28English475
Limitations of next-generation genome sequence assembly2010/11/21English474
Exploring the sequence determinants of amyloid structure using position-specific scoring matrices2010/02/14English473