Nature Methods

Title Publication Date Language Citations
Targeting and tracing antigens in live cells with fluorescent nanobodies2006/10/23English473
All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins2014/06/22English472
A large genome center's improvements to the Illumina sequencing system2008/11/25English472
Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy2014/05/18English466
Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data2008/08/17English464
CLARITY for mapping the nervous system2013/05/30English463
Acoustic tweezers for the life sciences2018/11/26English462
CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets2017/05/01English462
The fickle P value generates irreproducible results2015/02/26English460
Machine-learning-guided directed evolution for protein engineering2019/07/15English460
A nonviral minicircle vector for deriving human iPS cells2010/02/07English459
idTracker: tracking individuals in a group by automatic identification of unmarked animals2014/06/01English457
Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs2019/10/07English456
Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity2016/01/11English455
Real-time deformability cytometry: on-the-fly cell mechanical phenotyping2015/02/02English453
Martini 3: a general purpose force field for coarse-grained molecular dynamics2021/03/29English453
Bioconda: sustainable and comprehensive software distribution for the life sciences2018/07/01English453
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals2008/04/06English452
High-throughput ethomics in large groups of Drosophila2009/05/03English452
Unified rational protein engineering with sequence-based deep representation learning2019/10/21English452
Neural stem cells and neurospheres—re-evaluating the relationship2005/04/21English451
Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study2014/06/29English449
Deep learning enables cross-modality super-resolution in fluorescence microscopy2018/12/17English448
Measurement of mechanical tractions exerted by cells in three-dimensional matrices2010/11/14English445
Reproducible isolation of distinct, overlapping segments of the phosphoproteome2007/02/11English444
2b-RAD: a simple and flexible method for genome-wide genotyping2012/05/20English443
Integrated proteomic analysis of post-translational modifications by serial enrichment2013/06/09English443
High-speed label-free functional photoacoustic microscopy of mouse brain in action2015/03/30English442
Validation of noise models for single-cell transcriptomics2014/04/20English442
MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes2011/07/31English441