JCI Insight

Title Publication Date Language Citations
Rapamycin rescues loss of function in blood-brain barrier–interacting Tregs2024/04/08English
Ga11 deficiency increases fibroblast growth factor-23 levels in a mouse model of Familial Hypocalciuric Hypercalcemia2024/03/26English
Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease2024/02/15English
ORAI1 inhibition as an efficient preclinical therapy for tubular aggregate myopathy and Stormorken syndrome2024/03/05English
Transient inhibition of sodium-glucose cotransporter 2 after ischemia/reperfusion injury ameliorates chronic kidney disease2024/02/22English
Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome2024/02/20English
ctDNA transiting into urine is ultrashort and facilitates noninvasive liquid biopsy of HPV+ oropharyngeal cancer2024/02/08English
Complement protein signatures in patients with alcohol-associated hepatitis2024/04/04English
Heterogeneous SARS-CoV-2 kinetics due to variable timing and intensity of immune responses2024/04/04English
Improved mitochondrial function in the heart of sarcolipin-deficient dystrophin and utrophin double knockout mice2024/04/02English
Clonal hematopoiesis in people with advanced HIV and associated inflammatory syndromes2024/04/02English
HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ART2024/04/08English
A complement C4–derived glycopeptide is a biomarker for PMM2-CDG2024/04/08English
FLRT2 prevents endothelial cell senescence and vascular aging by regulating the ITGB4/mTORC2/p53 signaling pathway2024/04/08English
Single-cell molecular signature of pathogenic T helper subsets in type 2–associated disorders in humans2024/04/08English
Alkali injury–induced pathological lymphangiogenesis in the iris facilitates the infiltration of T cells and ocular inflammation2024/04/08English
Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance2024/04/08English
Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS2024/04/08English
Prophylactic efficacy of an intranasal spray with 2 synergetic antibodies neutralizing Omicron2024/04/08English
Atrogin-1 promotes muscle homeostasis by regulating levels of endoplasmic reticulum chaperone BiP2024/03/26English
Chimeric antigen receptor macrophages target and resorb amyloid plaques2024/02/06English
The spatially resolved transcriptome signatures of glomeruli in chronic kidney disease2024/03/22English
Diagnosis of malignant body fluids via cancer-universal methylation in cell-free DNA2024/04/08English
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early life prospective cohort2024/04/02English
Impaired innate and adaptive immune responses to BNT162b2 SARS-CoV-2 vaccination in systemic lupus erythematosus2024/03/08English
Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen2024/04/02English
Attenuation of HOIL-1L ligase activity promotes systemic autoimmune disorders by augmenting linear ubiquitin signaling2024/02/08English
Insulin regulation of regional lipolysis in upper-body obese and lean humans2024/04/11English
Predictors of HIV rebound differ by timing of antiretroviral therapy initiation2024/02/08English
Minnelide suppresses GVHD and enhances survival while maintaining GVT responses2024/04/11English