Nature Biotechnology

Title Publication Date Language Citations
Full-length transcriptome assembly from RNA-Seq data without a reference genome2011/05/15English13,961
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation2010/05/01English11,030
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification2008/11/30English10,065
Reproducible, interactive, scalable and extensible microbiome data science using QIIME 22019/07/24English9,621
Integrative genomics viewer2011/01/01English8,800
StringTie enables improved reconstruction of a transcriptome from RNA-seq reads2015/02/18English6,482
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences2013/08/25English6,423
Integrating single-cell transcriptomic data across different conditions, technologies, and species2018/04/02English5,829
Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype2019/08/01English5,077
Near-optimal probabilistic RNA-seq quantification2016/04/04English4,873
Principles of nanoparticle design for overcoming biological barriers to drug delivery2015/09/01English4,418
3D bioprinting of tissues and organs2014/08/01English4,210
Large-scale analysis of the yeast proteome by multidimensional protein identification technology2001/03/01English3,350
In vivo cancer targeting and imaging with semiconductor quantum dots2004/07/18English3,344
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells2014/03/23English3,271
Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering2005/01/01English3,221
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples2013/02/10English3,191
Renal clearance of quantum dots2007/09/23English3,161
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein2004/11/21English3,149
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes2011/03/20English3,119
Quantitative analysis of complex protein mixtures using isotope-coded affinity tags1999/10/01English3,055
DNA targeting specificity of RNA-guided Cas9 nucleases2013/07/21English3,051
Spatial reconstruction of single-cell gene expression data2015/04/13English2,955
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies2006/12/01English2,952
A clearer vision for in vivo imaging2001/04/01English2,910
GREAT improves functional interpretation of cis-regulatory regions2010/05/01English2,871
Molecular Beacons: Probes that Fluoresce upon Hybridization1996/03/01English2,797
An economic method for the fluorescent labeling of PCR fragments2000/02/01English2,792
Nonlinear magic: multiphoton microscopy in the biosciences2003/10/31English2,593
SignalP 5.0 improves signal peptide predictions using deep neural networks2019/02/18English2,584