Title	Publication Date	Language	Citations
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays	1999/04/01	English	5,061
High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery	2001/12/01	English	631
The Use of 3-D Cultures for High-Throughput Screening: The Multicellular Spheroid Model	2004/06/01	English	534
Three-Dimensional Cell Cultures in Drug Discovery and Development	2017/06/01	English	511
Rapid Generation of Single-Tumor Spheroids for High-Throughput Cell Function and Toxicity Analysis	2006/12/01	English	404
Improved Statistical Methods for Hit Selection in High-Throughput Screening	2003/12/01	English	219
Fluorescence Polarization and Anisotropy in High Throughput Screening: Perspectives and Primer	2000/10/01	English	214
Using Extended-Connectivity Fingerprints with Laplacian-Modified Bayesian Analysis in High-Throughput Screening Follow-Up	2005/10/01	English	208
A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm	2016/01/01	English	199
Chagas Disease Drug Discovery: Toward a New Era	2015/01/01	English	194
A Perspective on the Kinetics of Covalent and Irreversible Inhibition	2017/01/01	English	189
Label-Free Assays on the BIND System	2004/09/01	English	176
IonWorks™ HT: A New High-Throughput Electrophysiology Measurement Platform	2003/01/01	English	168
A New Bliss Independence Model to Analyze Drug Combination Data	2014/06/01	English	166
Technical Notes: A Simple Technique for Reducing Edge Effect in Cell-Based Assays	2003/10/01	English	165
Dynamic Monitoring of Cell Adhesion and Spreading on Microelectronic Sensor Arrays	2005/12/01	English	163
High Throughput Prediction of Oral Absorption: Improvement of the Composition of the Lipid Solution Used in Parallel Artificial Membrane Permeation Assay	2001/06/01	English	152
Development of High Throughput Screening Assays Using Fluorescence Polarization: Nuclear Receptor-Ligand–Binding and Kinase /Phosphatase Assays	2000/04/01	English	152
A Comparison of Assay Performance Measures in Screening Assays: Signal Window, Z′ Factor, and Assay Variability Ratio	2006/04/01	English	152
Comparison of the Usefulness of the MTT, ATP, and Calcein Assays to Predict the Potency of Cytotoxic Agents in Various Human Cancer Cell Lines	2004/09/01	English	151
A Reliable Tool to Determine Cell Viability in Complex 3-D Culture: The Acid Phosphatase Assay	2007/10/01	English	150
The Future of High-Throughput Screening	2008/07/01	English	147
Fluorescence Polarization Competition Assay: The Range of Resolvable Inhibitor Potency Is Limited by the Affinity of the Fluorescent Ligand	2003/01/01	English	146
E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones	2021/04/01	English	144
Screening β-Arrestin Recruitment for the Identification of Natural Ligands for Orphan G-Protein–Coupled Receptors	2013/06/01	English	138
An AlphaScreen®-Based Assay for High-Throughput Screening for Specific Inhibitors of Nuclear Import	2011/02/01	English	131
Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability	2016/06/01	English	130
Increasing the Content of High-Content Screening: An Overview	2014/06/01	English	129
FLIPR: A New Instrument for Accurate, High Throughput Optical Screening	1996/03/01	English	129
Illustration of SSMD, z Score, SSMD*, z* Score, and t Statistic for Hit Selection in RNAi High-Throughput Screens	2011/08/01	English	126