Molecular Therapy

Title Publication Date Language Citations
Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB22010/04/01English1,738
Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells2013/01/01English1,145
A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes2010/09/01English1,080
Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability2008/11/01English951
Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain2011/10/01English949
Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection2008/06/01English933
A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy2005/06/01English825
Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo2009/08/01English824
Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications2015/05/01English753
Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms2010/07/01English746
T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis2011/03/01English698
Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes2005/09/01English649
Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery2019/04/01English610
Cellular Uptake of Arginine-Rich Peptides: Roles for Macropinocytosis and Actin Rearrangement2004/12/01English590
Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation2012/01/01English581
Lipid Nanoparticle Systems for Enabling Gene Therapies2017/07/01English579
Adeno-associated Virus Serotypes: Vector Toolkit for Human Gene Therapy2006/09/01English567
Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer2008/04/01English558
Effect of Genome Size on AAV Vector Packaging2010/01/01English554
The Possible “Proton Sponge ” Effect of Polyethylenimine (PEI) Does Not Include Change in Lysosomal pH2013/01/01English528
Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System2004/08/01English519
The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls2010/03/01English509
Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation2012/01/01English494
Treatment of Metastatic Renal Cell Carcinoma With CAIX CAR-engineered T cells: Clinical Evaluation and Management of On-target Toxicity2013/04/01English485
Codon-Optimized Gaussia Luciferase cDNA for Mammalian Gene Expression in Culture and in Vivo2005/03/01English465
Adenoviruses as vaccine vectors2004/10/01English459
Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice2011/06/01English458
FDA-Approved Oligonucleotide Therapies in 20172017/05/01English453
Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis2013/07/01English448
Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV82006/07/01English438