Bioorganic Chemistry

Title Publication Date Language Citations
Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs2020/07/01English124
History of the development of antifungal azoles: A review on structures, SAR, and mechanism of action2020/11/01English124
Recent advancements of coumarin-based anticancer agents: An up-to-date review2020/10/01English122
Synthetic and medicinal perspective of thiazolidinones: A review2017/12/01English120
Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers2019/07/01English120
Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions2017/10/01English119
Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease2015/10/01English117
The first synthesis of 4-phenylbutenone derivative bromophenols including natural products and their inhibition profiles for carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase enzymes2017/06/01English116
Novel 1,2,4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies2018/02/01English115
Innovative nano-carriers in anticancer drug delivery-a comprehensive review2019/04/01English115
Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes2019/05/01English114
Hydroxytyrosol lipophilic analogues: Enzymatic synthesis, radical scavenging activity and DNA oxidative damage protection2007/04/01English114
Design and synthesis of novel quinazolinone-1,2,3-triazole hybrids as new anti-diabetic agents: In vitro α-glucosidase inhibition, kinetic, and docking study2019/03/01English114
Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials2018/12/01English114
Quinolines, a perpetual, multipurpose scaffold in medicinal chemistry2021/04/01English111
Carbonic anhydrase inhibitory properties of novel benzylsulfamides using molecular modeling and experimental studies2014/10/01English111
Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers2020/01/01English111
Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes2019/02/01English110
Synthesis, in vitro evaluation and molecular docking studies of thiazole derivatives as new inhibitors of α-glucosidase2015/10/01English110
Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors2019/08/01English109
The role of long noncoding RNA in major human disease2019/11/01English109
Promising anti-inflammatory effects of chalcones via inhibition of cyclooxygenase, prostaglandin E2, inducible NO synthase and nuclear factor κb activities2019/06/01English107
Design, synthesis, characterization, antimicrobial evaluation and molecular modeling studies of some dehydroacetic acid-chalcone-1,2,3-triazole hybrids2018/04/01English107
“Induced-fit”-type complex formation of the model enzyme α-cyclodextrin1976/06/01English105
Synthesis, molecular docking and anti-inflammatory screening of novel quinoline incorporated pyrazole derivatives using the Pfitzinger reaction II2015/02/01English105
Design, synthesis, molecular modeling and biological evaluation of novel 1H-pyrazolo[3,4-b]pyridine derivatives as potential anticancer agents2016/08/01English104
Estrogen receptor agonists/antagonists in breast cancer therapy: A critical review2017/04/01English104
The crystal and molecular structure of quercetin: A biologically active and naturally occurring flavonoid1986/03/01English104
Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity2019/03/01English103
Encapsulation of ciprofloxacin within modified xanthan gum- chitosan based hydrogel for drug delivery2019/03/01English103