Bioorganic Chemistry

Title Publication Date Language Citations
Antioxidant aromatic compounds from Amomum villosum and target prediction of active ingredientsEnglish
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitorsEnglish
Discovery of 4-phenyl-1H-indazole derivatives as novel small-molecule inhibitors targeting the PD-1/PD-L1 interactionEnglish
Exploring cyclopropylamine containing cyanopyrimidines as LSD1 inhibitors: Design, synthesis, ADMET, MD analysis and anticancer activity profilingEnglish
Dried tangerine peel polysaccharide (DTPP) alleviates hepatic steatosis by suppressing TLR4/MD-2-mediated inflammation and endoplasmic reticulum stressEnglish
Novel Pt(IV) complexes containing salvigenin ligand reverse cisplatin-induced resistance by inhibiting Rap1b-mediated cancer cell stemness in esophageal squamous cell carcinoma treatmentsEnglish
Synthesis and bio-evaluation of newer dihydropyridines and tetrahydropyridines based glycomimetic azasugars2024/04/01English
Identification of new 5-(2,6-dichlorophenyl)-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-7-carboxylic acids as p38α MAPK inhibitors: Design, synthesis, antitumor evaluation, molecular docking and in silico studies2024/04/01English
The antimicrobial potential of adarotene derivatives against Staphylococcus aureus strains2024/04/01English
Synthesis and evaluation of novel N1-acylated 5-(4-pyridinyl)indazole derivatives as potent and selective haspin inhibitors2024/04/01English
Hybrid pharmacophore design and synthesis of donepezil-inspired aurone derivative salts as multifunctional acetylcholinesterase inhibitors2024/04/01English
Structural optimization and biological evaluation of ML364 based derivatives as USP2a inhibitors2024/04/01English
Effect of N-o-nitrobenzylation on conformation and membrane permeability of linear peptides2024/04/01English
A novel NIR fluorescent probe inhibits melanoma progression through apoptosis and ERK/DRP1-mediated mitochondrial fission2024/04/01English
Astraoleanosides E–P, oleanane-type triterpenoid saponins from the aerial parts of Astragalus membranaceus Bunge and their β-glucuronidase inhibitory activity2024/04/01English
Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient2024/04/01English
Synthesis and structure-activity relationship studies of fusidic acid derivatives as anti-inflammatory agents for acute lung injury2023/12/01English
Conjugates of nucleobases with triazole-hydroxamic acids for the reactivation of acetylcholinesterase and treatment of delayed neurodegeneration induced by organophosphate poisoning2023/12/01English
Design, synthesis and anti-osteosarcoma activity study of novel pyrido[2,3-d]pyrimidine derivatives by inhibiting DKK1-Wnt/β-catenin pathway2023/12/01English
Oligomeric phloroglucinols with hAChE inhibitory and antibacterial activities from tropic Rhodomyrtus tomentosa2023/12/01English
Exploration of the novel phthalimide-hydroxypyridinone derivatives as multifunctional drug candidates against Alzheimer’s disease2023/12/01English
Combination of quinoxaline with pentamethinium system: Mitochondrial staining and targeting2023/12/01English
Synthesis and structure–activity relationship study of phenoxybenzylpiperazine analogues as CCR8 agonists2023/10/01English
Discovery of small molecule β-catenin suppressors that enhance immunotherapy2023/10/01English
Synthesis and clinical application of small-molecule inhibitors and PROTACs of anaplastic lymphoma kinase2023/11/01English
Editorial Board2023/10/01English
Peripheral substitution effects on unnatural base pairs: A case of brominated TPT3 to enhance replication fidelity2023/11/01English
Issue TOC2023/10/01English
Design and synthesis of 9-phenanthranilamide derivatives and the study of anti-inflammatory, antioxidant and neuroprotective activities2023/12/01English
Fluoroalkoxylated C-3 and C-9 (S)-12-bromostepholidine analogues with D1R antagonist activity2023/12/01English