Bioorganic Chemistry

Title Publication Date Language Citations
Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of PLK12023/10/01English
Novel thiazolopyridine derivatives of diflapolin as dual sEH/FLAP inhibitors with improved solubility2023/10/01English
Synthesis and characterization of chemical engineered PLGA nanosphere: Triggering mechanism of Catechol-O-methyltransferase inhibition on in vivo neurodegeneration2023/10/01English
Synthesis, characterization and hypolipidemic effects of urazine derivatives on rat: Study of molecular modeling and enzyme inhibition2023/10/01English
Issue TOC2023/02/01English
Editorial Board2023/02/01English
Editorial Board2023/03/01English
Synthesis and evaluation of pentacyclic triterpenoids conjugates as novel HBV entry inhibitors targeting NTCP receptorEnglish
Discovery of digallic acid as XOD/URAT1 dual target inhibitor for the treatment of hyperuricemiaEnglish
A path from synthesis to emergency use authorization of molnupiravir as a COVID-19 therapyEnglish
Discovery of new 2-(3-(naphthalen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigationsEnglish
Impact of GSK-3β and CK-1δ on Wnt signaling pathway in alzheimer disease: A dual target approachEnglish
Leucine zipper as a bridge for transaminase self-assembly: A fusion enzyme for efficient chiral conversion of d-phenylglycineEnglish
Non-peptidic inhibitors targeting SARS-CoV-2 main protease: A reviewEnglish
Synthesis and preclinical evaluation of a novel probe [18F]AlF-NOTA-IPB-GPC3P for PET imaging of GPC3 positive tumorEnglish
Dual site reactivity of indole-3-Schiff bases with S/Se/Cl substituted ketenes for stereoselective C-4 substituted indole-β-lactams, biological evaluations, magic chloro effect and molecular docking studiesEnglish
Design, synthesis, and biological evaluation of cathepsin B cleavage albumin-binding SN38 prodrug in breast cancerEnglish
Synthesis and biological evaluation of Halogen-Substituted novel α-Ketoamides as potential protein aggregation modulators in Alzheimer’s diseaseEnglish
13-Oxyingenol-dodecanoate inhibits the growth of non-small cell lung cancer cells by targeting ULK1English
Lathyrane and premyrsinane Euphorbia diterpenes against Alzheimer's disease: Bioinspired synthesis, anti-cholinesterase and neuroprotection bioactivityEnglish
Discovery of novel HER2 targeting peptide-camptothecin conjugates with effective suppression for selective cancer treatmentEnglish
Label-free cell phenotypic profiling of histamine H4R receptor and discovery of non-competitive H4R antagonist from natural productsEnglish
Research progress of PROTACs for neurodegenerative diseases therapyEnglish
Design, synthesis, and evaluation of antitumor activity of Mobocertinib derivatives, a third-generation EGFR inhibitorEnglish
Exploring novel indazole derivatives as ASK1 inhibitors: Design, synthesis, biological evaluation and docking studiesEnglish
Exploring long-range fluorine–carbon J-coupling for conformational analysis of deoxyfluorinated disaccharides: A combined computational and NMR studyEnglish
Natural products from Odontonema strictum promote neurite outgrowth in neuronal PC12 cellsEnglish
Design, synthesis, in vitro and in silico evaluations of new isatin-triazine- aniline hybrids as potent anti- Alzheimer multi-target directed lead compoundsEnglish
Inhibition of TGF-β1/Smad3 signaling by compound 5aa: A potential treatment for idiopathic pulmonary fibrosisEnglish
Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitorsEnglish