mAbs

Title Publication Date Language Citations
2011 upcoming meetings2011/05/01English
Note of appreciation to reviewers2017/12/20English
10th antibody industrial symposium: new developments in antibody and adoptive cell therapies2023/05/15English
Production of antibodies and antibody fragments containing non-natural amino acids in Escherichia coli2024/02/21English
Facilitating high throughput bispecific antibody production and potential applications within biopharmaceutical discovery workflows2024/02/21English
Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-22024/04/09English
Accelerating the speed of innovative anti-tumor drugs to first-in-human trials incorporating key de-risk strategies2023/12/14English
Determining the affinities of high-affinity antibodies using KinExA and surface plasmon resonance2023/12/13English
Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C λ interface2023/11/06English
T and B cell epitope analysis for the immunogenicity evaluation and mitigation of antibody-based therapeutics2024/03/21English
Do antibody CDR loops change conformation upon binding?2024/03/13English
Predicting deamidation and isomerization sites in therapeutic antibodies using structure-based in silico approaches2024/03/28English
In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies2024/03/27English
Evaluation of the impact of antibody fragments on aggregation of intact molecules via size exclusion chromatography coupled with native mass spectrometry2024/03/27English
Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces2024/03/18English
Reduction of monoclonal antibody viscosity using interpretable machine learning2024/03/12English
RUBY® – a tetravalent (2+2) bispecific antibody format with excellent functionality and IgG-like stability, pharmacology and developability properties2024/03/25English
Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability2024/02/14English
High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions2023/03/01English
Interactions of the anti-FcRn monoclonal antibody, rozanolixizumab, with Fcγ receptors and functional impact on immune cells in vitro2024/01/19English
Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG 1 antibody2024/01/25English
Bivalent non-human gal-α1-3-gal glycan epitopes in the Fc region of a monoclonal antibody model can be recognized by anti-Gal-α1-3-Gal IgE antibodies2023/07/27English
Can antibodies be “vegan”? A guide through the maze of today’s antibody generation methods2024/04/18English
Targeted CQA analytical control strategy for commercial antibody products: Replacing ion-exchange chromatography methods for charge heterogeneity with multi-attribute monitoring2024/04/23English
Alternative splicing for tuneable expression of protein subunits at desired ratios2024/04/22English
Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody2024/04/18English
Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers2024/02/19English
Identification of tyrosine sulfation in the variable region of a bispecific antibody and its effect on stability and biological activity2023/09/24English
Interplay of heavy chain introns influences efficient transcript splicing and affects product quality of recombinant biotherapeutic antibodies from CHO cells2023/08/09English
Use of poxvirus display to select antibodies specific for complex membrane antigens2023/08/27English