Want to explore the intersection of physics and biology? This review delves into the fascinating world of microfluidics, revealing how fluid behavior at the microscale can be harnessed for biological applications. It outlines the physics governing microfluidics, including surface tension, viscosity, and laminar flow, offering a solid foundation for understanding device design and function. This foundational understanding is leveraged in the design and fabrication of devices that manipulate fluids at this scale. The review explores common fabrication methods, like soft lithography and etching, enabling researchers to construct intricate microfluidic systems. It also examines crucial components such as valves, mixers, and pumps engineered to control fluid flow with precision. Sensing techniques used to monitor flow dynamics are highlighted, providing feedback mechanisms for optimized performance. This comprehensive overview illustrates microfluidics' significant contributions to biological studies, with examples of devices and systems used in bioanalysis. By leveraging the physics of the microscale, microfluidics offers innovative solutions for various life science applications. It also opens avenues for advanced diagnostics and personalized medicine, highlighting its potential for future scientific advancements.
Published in the 'Annual Review of Biomedical Engineering,' this paper aligns with the journal's focus on innovative technologies for biological studies. The use of microfluidics to create functional components helps push forward medical technology, a core area for the journal. Its references and citations connect it to other works in related fields, reinforcing its significance within the biomedical engineering community.
| Category | Category Repetition |
|---|---|
| Science: Chemistry | 493 |
| Technology: Chemical technology | 448 |
| Science: Chemistry: Analytical chemistry | 327 |
| Science: Physics | 314 |
| Science: Mathematics: Instruments and machines | 274 |