Human Gene Therapy

Title Publication Date Language Citations
The Regulation of Differentiation in Mesenchymal Stem Cells2010/10/01English256
Mutagenesis and Oncogenesis by Chromosomal Insertion of Gene Transfer Vectors2006/03/01English256
Gene Therapy for the Treatment of Brain Tumors Using Intra-Tumoral Transduction with the Thymidine Kinase Gene and Intravenous Ganciclovir. National Institutes of Health1993/02/01English254
Efficient Construction of a Recombinant Adenovirus Vector by an ImprovedIn VitroLigation Method1998/11/20English251
Optimizing Promoters for Recombinant Adeno-Associated Virus-Mediated Gene Expression in the Peripheral and Central Nervous System Using Self-Complementary Vectors2011/09/01English250
Current Status of Gendicine in China: Recombinant Human Ad-p53 Agent for Treatment of Cancers2005/09/01English240
Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing α1-Antitrypsin: Interim Results2011/10/01English240
Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale2010/10/01English239
A Pilot Study ofIn VivoLiver-Directed Gene Transfer with an Adenoviral Vector in Partial Ornithine Transcarbamylase Deficiency2002/01/01English237
Highly Purified Recombinant Adeno-Associated Virus Vectors Are Biologically Active and Free of Detectable Helper and Wild-Type Viruses1999/04/10English235
Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses2015/07/01English232
Direct Gene Transfer into Skeletal MuscleIn Vivo: Factors Affecting Efficiency of Transfer and Stability of Expression1993/04/01English229
An Improved Plasmid DNA Expression Vector for Direct Injection into Skeletal Muscle1996/07/01English227
Adenovirus-Mediated Transfer of the CFTR Gene to Lung of Nonhuman Primates: Toxicity Study1993/12/01English224
Adenovirus: The First EffectiveIn VivoGene Delivery Vector2014/01/01English222
Promoter Attenuation in Gene Therapy: Interferon-γand Tumor Necrosis Factor-αInhibit Transgene Expression1997/11/20English221
A Novel Three-Pronged Approach to Kill Cancer Cells Selectively: Concomitant Viral, Double Suicide Gene, and Radiotherapy1998/06/10English219
A Simple Method for Constructing E1- and E1/E4-Deleted Recombinant Adenoviral Vectors1999/08/10English218
Ultrasound-Mediated Transfection of Mammalian Cells1996/07/10English215
Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Gene Therapy in Patients with Localized Malignancy: Results of a Phase I Clinical Trial in Malignant Mesothelioma1998/05/01English215
Recognition of Glioma Stem Cells by Genetically Modified T Cells Targeting EGFRvIII and Development of Adoptive Cell Therapy for Glioma2012/10/01English214
Isolation of Highly Infectious and Pure Adeno-Associated Virus Type 2 Vectors with a Single-Step Gravity-Flow Column2001/01/01English214
Selective and Rapid Uptake of Adeno-Associated Virus Type 2 in Brain1998/05/20English211
Assessment of Recombinant Adenoviral Vectors for Hepatic Gene Therapy1993/08/01English211
In Vivo Nasal Potential Difference: Techniques and Protocols for Assessing Efficacy of Gene Transfer in Cystic Fibrosis1995/04/01English211
Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates2012/04/01English211
Replicative Potential and Telomere Length in Human Skeletal Muscle: Implications for Satellite Cell-Mediated Gene Therapy1997/08/10English210
Comparative Analysis of Adeno-Associated Viral Vector Serotypes 1, 2, 5, 7, And 8 in Mouse Brain2007/03/01English209
Treatment with Intramuscular Vascular Endothelial Growth Factor Gene Compared with Placebo for Patients with Diabetes Mellitus and Critical Limb Ischemia: A Double-Blind Randomized Trial2006/06/01English207
Retrovirus Packaging Cells1990/04/01English206