Title	Publication Date	Language	Citations
High Levels of Foreign Gene Expression in Hepatocytes after Tail Vein Injections of Naked Plasmid DNA	1999/07/01	English	690
Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors	2010/06/01	English	660
Treatment of Leber Congenital Amaurosis Due toRPE65Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial	2008/10/01	English	609
Episomal Vectors Rapidly and Stably Produce High-Titer Recombinant Retrovirus	1996/08/01	English	596
Severe Toxicity in Nonhuman Primates and Piglets Following High-Dose Intravenous Administration of an Adeno-Associated Virus Vector Expressing Human SMN	2018/03/01	English	476
Novel Tools for Production and Purification of Recombinant Adenoassociated Virus Vectors	1998/12/10	English	461
A Phase III Clinical Evaluation of Herpes Simplex Virus Type 1 Thymidine Kinase and Ganciclovir Gene Therapy as an Adjuvant to Surgical Resection and Radiation in Adults with Previously Untreated Glioblastoma Multiforme	2000/11/20	English	414
A Powerful Nonviral Vector for In Vivo Gene Transfer into the Adult Mammalian Brain: Polyethylenimine	1996/10/20	English	395
Nonviral Vectors in the New Millennium: Delivery Barriers in Gene Transfer	2001/05/20	English	394
High-Level Transduction and Gene Expression in Hematopoietic Repopulating Cells Using a Human Imunodeficiency Virus Type 1-Based Lentiviral Vector Containing an Internal Spleen Focus Forming Virus Promoter	2002/05/01	English	391
Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery	1996/08/01	English	391
Characterization of 911: A New Helper Cell Line for the Titration and Propagation of Early Region 1-Deleted Adenoviral Vectors	1996/01/20	English	373
Innate Immune Mechanisms Dominate Elimination of Adenoviral Vectors FollowingIn VivoAdministration	1997/01/01	English	362
Quantitative Analysis of the Packaging Capacity of Recombinant Adeno-Associated Virus	1996/11/10	English	353
Insect Cells as a Factory to Produce Adeno-Associated Virus Type 2 Vectors	2002/11/01	English	330
Adenoviral Gene Therapy Leads to Rapid Induction of Multiple Chemokines and Acute Neutrophil-Dependent Hepatic Injury in Vivo	1999/04/10	English	327
Detailed Analysis of Structures and Formulations of Cationic Lipids for Efficient Gene Transfer to the Lung	1996/09/10	English	321
Nonviral Gene Therapy: The Promise of Genes as Pharmaceutical Products	1995/09/01	English	307
New Helper Cells and Matched Early Region 1-Deleted Adenovirus Vectors Prevent Generation of Replication-Competent Adenoviruses	1998/09/01	English	305
The Innate Immune Response to Adenovirus Vectors	2004/12/01	English	297
Systematic Determination of the Packaging Limit of Lentiviral Vectors	2001/10/10	English	297
Gene Therapy by Intramuscular Injection of Plasmid DNA: Studies on Firefly Luciferase Gene Expression in Mice	1993/08/01	English	293
Nomenclature for Synthetic Gene Delivery Systems	1997/03/20	English	289
PEGylation of Adenovirus with Retention of Infectivity and Protection from Neutralizing Antibody in Vitro and in Vivo	1999/05/20	English	288
Bone Marrow Mesenchymal Stem Cells: Historical Overview and Concepts	2010/09/01	English	284
Treatment of Late Infantile Neuronal Ceroid Lipofuscinosis by CNS Administration of a Serotype 2 Adeno-Associated Virus Expressing CLN2 cDNA	2008/05/01	English	275
Improved Methods of Retroviral Vector Transduction and Production for Gene Therapy	1994/01/01	English	271
In VitroEvidence That Metabolic Cooperation Is Responsible for the Bystander Effect Observed with HSVtkRetroviral Gene Therapy	1993/12/01	English	271
Silencing and Variegation of Gammaretrovirus and Lentivirus Vectors	2005/11/01	English	263
Characterization of Vectors for Gene Therapy Formed by Self-Assembly of DNA with Synthetic Block Co-Polymers	1996/11/10	English	257