Chemical Research in Toxicology

Title Publication Date Language Citations
Enantioselective Environmental Toxicology of Chiral Pesticides2015/02/02English133
Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space2016/03/14English133
Chloropyridinyl Neonicotinoid Insecticides:  Diverse Molecular Substituents Contribute to Facile Metabolism in Mice2006/06/08English133
The role of calcium in cell killing1990/11/01English133
Genistein Inhibits Advanced Glycation End Product Formation by Trapping Methylglyoxal2011/02/23English132
Metabolic Activation of Pyrrolizidine Alkaloids: Insights into the Structural and Enzymatic Basis2014/05/22English132
Identification of 14 Quercetin Phase II Mono- and Mixed Conjugates and Their Formation by Rat and Human Phase II in Vitro Model Systems2004/10/28English132
Sulfur-Containing Arsenical Mistaken for Dimethylarsinous Acid [DMA(III)] and Identified as a Natural Metabolite in Urine:  Major Implications for Studies on Arsenic Metabolism and Toxicity2004/07/17English132
Detection and Identification of Metabolites of Microcystins Formed in Vivo in Mouse and Rat Livers1996/01/01English132
Profiling 976 ToxCast Chemicals across 331 Enzymatic and Receptor Signaling Assays2013/05/16English132
Chemistry and Biology of DNA Containing 1,N2-Deoxyguanosine Adducts of the α,β-Unsaturated Aldehydes Acrolein, Crotonaldehyde, and 4-Hydroxynonenal2009/04/27English131
Disruption of the Arsenic (+3 Oxidation State) Methyltransferase Gene in the Mouse Alters the Phenotype for Methylation of Arsenic and Affects Distribution and Retention of Orally Administered Arsenate2009/08/20English131
Methylarsenicals and Arsinothiols Are Potent Inhibitors of Mouse Liver Thioredoxin Reductase1999/09/09English131
Catalytic Scavenging of Peroxynitrite by Isomeric Mn(III) N-Methylpyridylporphyrins in the Presence of Reductants1999/04/30English131
Carbon Dioxide:  Physiological Catalyst for Peroxynitrite-Mediated Cellular Damage or Cellular Protectant?1996/01/01English130
Effects of Smoking Cessation on Eight Urinary Tobacco Carcinogen and Toxicant Biomarkers2009/03/25English130
Effect of Ambient PM2.5 on Lung Mitochondrial Damage and Fusion/Fission Gene Expression in Rats2015/01/16English129
Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline1993/09/01English129
Mechanisms of Troglitazone Hepatotoxicity2003/05/06English129
Characterization and quantitation of urinary metabolites of [1,2,3-13C]acrylamide in rats and mice using carbon-13 nuclear magnetic resonance spectroscopy1992/01/01English128
Metabolism and Toxicity of Drugs. Two Decades of Progress in Industrial Drug Metabolism2007/12/04English128
Surface Modification of Quartz Inhibits Toxicity, Particle Uptake, and Oxidative DNA Damage in Human Lung Epithelial Cells2002/08/24English127
Identification of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA1992/09/01English126
Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide1992/09/01English125
Biomarkers in Toxicology and Risk Assessment: Informing Critical Dose–Response Relationships2007/12/28English125
Mammalian synthesis of nitrite, nitrate, nitric oxide, and N-nitrosating agents1988/09/01English125
Skin Sensitization:  Reaction Mechanistic Applicability Domains for Structure−Activity Relationships2005/08/20English125
G-Quadruplex Folds of the Human Telomere Sequence Alter the Site Reactivity and Reaction Pathway of Guanine Oxidation Compared to Duplex DNA2013/03/13English124
The role of oxidative damage in metal carcinogenicity1991/11/01English123
Reaction of Singlet Oxygen with 2'-Deoxyguanosine and DNA. Isolation and Characterization of the Main Oxidation Products1995/04/01English123