Chemical Research in Toxicology

Title Publication Date Language Citations
The ozonation of unsaturated fatty acids: aldehydes and hydrogen peroxide as products and possible mediators of ozone toxicity1991/05/01English123
Serum Metabolomics Reveals Irreversible Inhibition of Fatty Acid β-Oxidation through the Suppression of PPARα Activation as a Contributing Mechanism of Acetaminophen-Induced Hepatotoxicity2009/03/03English123
Cytotoxicity and Genotoxicity of Size-Fractionated Iron Oxide (Magnetite) in A549 Human Lung Epithelial Cells: Role of ROS, JNK, and NF-κB2011/07/18English123
DNA Damage Caused by Metal Nanoparticles: Involvement of Oxidative Stress and Activation of ATM2012/05/14English123
Ultrafine NiO Particles Induce Cytotoxicity in Vitro by Cellular Uptake and Subsequent Ni(II) Release2009/07/27English122
Co(II) and Cd(II) Substitute for Zn(II) in the Zinc Finger Derived from the DNA Repair Protein XPA, Demonstrating a Variety of Potential Mechanisms of Toxicity2004/10/05English122
Metallothionein and other cadmium-binding proteins: recent developments1990/07/01English122
Pyrrole formation from 4-hydroxynonenal and primary amines1993/01/01English122
Human Cytochrome P450 2E1 Is a Major Autoantigen Associated with Halothane Hepatitis1996/01/01English122
Vascular Endothelial Cells Generate Peroxynitrite in Response to Carbon Monoxide Exposure1997/09/01English122
Quercetin, Resveratrol, and Curcumin Are Indirect Activators of the Aryl Hydrocarbon Receptor (AHR)2012/08/28English122
p53 Signaling and Cell Cycle Checkpoints2001/02/07English122
Multi-Omics Reveals that Lead Exposure Disturbs Gut Microbiome Development, Key Metabolites, and Metabolic Pathways2017/03/16English121
Metabonomic Deconvolution Of Embedded Toxicity:  Application To Thioacetamide Hepato- and Nephrotoxicity2005/03/24English121
Mechanism-Based Inactivation of Human Cytochromes P450s: Experimental Characterization, Reactive Intermediates, and Clinical Implications2007/12/04English120
Determination of 8-Oxoguanine in DNA by Gas Chromatography-Mass Spectrometry and HPLC-Electrochemical Detection: Overestimation of the Background Level of the Oxidized Base by the Gas Chromatography-Mass Spectrometry Assay1995/12/01English120
Metabonomic Characterization of Genetic Variations in Toxicological and Metabolic Responses Using Probabilistic Neural Networks2001/01/23English120
Structural Basis of the Antagonism between Inorganic Mercury and Selenium in Mammals2000/09/29English120
Can In Vitro Metabolism-Dependent Covalent Binding Data in Liver Microsomes Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis of 18 Drugs with Consideration of Intrinsic Clearance and Daily Dose2008/08/09English120
Quantitation of 8-Oxoguanine and Strand Breaks Produced by Four Oxidizing Agents1997/04/01English120
Doxorubicin Metabolism and Toxicity in Human Myocardium:  Role of Cytoplasmic Deglycosidation and Carbonyl Reduction2000/04/14English120
Future of ToxicologyIron Chelators and Differing Modes of Action and Toxicity:  The Changing Face of Iron Chelation Therapy2007/04/03English119
Cardiotoxicity of Antitumor Drugs2008/04/01English119
15-Deoxy-Δ12,14-prostaglandin J2: An Electrophilic Trigger of Cellular Responses2007/12/04English119
Toxicity of Multiwalled Carbon Nanotubes with End Defects Critically Depends on Their Functionalization Density2011/10/18English119
4-Oxo-2-nonenal Is Both More Neurotoxic and More Protein Reactive than 4-Hydroxy-2-nonenal2005/07/06English118
Antioxidant Chemistry of Green Tea Catechins. New Oxidation Products of (−)-Epigallocatechin Gallate and (−)-Epigallocatechin from Their Reactions with Peroxyl Radicals2000/08/11English118
Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage2016/11/07English118
Polycyclic Aromatic Hydrocarbons in the Mainstream Smoke of Popular U.S. Cigarettes2015/07/30English118
Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?2012/02/21English118