Journal of Medicinal Chemistry

Title Publication Date Language Citations
Basis for Design and Development of Platinum(IV) Anticancer Complexes2007/06/28English370
Peptide quantitative structure-activity relationships, a multivariate approach1987/07/01English369
Identification and Prediction of Promiscuous Aggregating Inhibitors among Known Drugs2003/09/13English368
α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment2020/02/11English368
Phenethylthiazolethiourea (PETT) Compounds, a New Class of HIV-1 Reverse Transcriptase Inhibitors. 1. Synthesis and Basic Structure-Activity Relationship Studies of PETT Analogs1995/12/01English368
CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure2015/01/06English367
Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight2020/07/01English367
A New Series of PDGF Receptor Tyrosine Kinase Inhibitors: 3-Substituted Quinoline Derivatives1994/07/01English367
Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors1995/08/01English366
Copper chelates as possible active forms of the antiarthritic agents1976/01/01English366
Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors2019/12/10English366
Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents1992/08/01English365
Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity1991/01/01English365
Synthesis and Antimycobacterial Activity of Pyrazine and Quinoxaline Derivatives2002/11/07English364
Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/62005/03/02English362
Molecular Similarity in Medicinal Chemistry2013/11/11English362
Metabolic and Pharmaceutical Aspects of Fluorinated Compounds2020/03/17English362
Folate-Targeted Therapies for Cancer2010/07/28English361
Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase2011/09/21English359
Structural and Functional Basis of Cyclooxygenase Inhibition2007/03/07English357
Antitumor Benzothiazoles. 16. Synthesis and Pharmaceutical Properties of Antitumor 2-(4-Aminophenyl)benzothiazole Amino Acid Prodrugs2001/12/20English355
Synthesis and Antiinflammatory Activity of Coumarin Derivatives,2005/09/13English354
A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs2003/03/01English353
6-Alkylamino- and 2,3-Dihydro-3‘-methoxy-2-phenyl-4-quinazolinones and Related Compounds:  Their Synthesis, Cytotoxicity, and Inhibition of Tubulin Polymerization2000/10/28English352
Assessing Scoring Functions for Protein−Ligand Interactions2004/05/04English351
Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria2010/06/22English351
Nitro-Group-Containing Drugs2018/10/08English349
Structure-activity relationships of antibacterial 6,7- and 7,8-disubstituted 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids1980/12/01English347
Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast Cancer2014/07/10English347
Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives1991/08/01English347