Alternatives to Laboratory Animals

Titel Veröffentlichungsdatum Sprache Zitate
Current Status of Methods for Defining the Applicability Domain of (Quantitative) Structure-Activity Relationships2005/04/01English467
QSAR Applicability Domain Estimation by Projection of the Training Set in Descriptor Space: A Review2005/10/01English397
A Multicompartmental Dynamic Computer-controlled Model Simulating the Stomach and Small Intestine1995/03/01English371
Chicken Egg Yolk Antibodies (IgY-technology): A Review of Progress in Production and Use in Research and Human and Veterinary Medicine2005/04/01English212
The ECVAM International Validation Study on In Vitro Embryotoxicity Tests: Results of the Definitive Phase and Evaluation of Prediction Models2002/03/01English210
Validation of the Embryonic Stem Cell Test in the International ECVAM Validation Study on Three In Vitro Embryotoxicity Tests2004/09/01English202
A Gold Standard Publication Checklist to Improve the Quality of Animal Studies, to Fully Integrate the Three Rs, and to Make Systematic Reviews More Feasible2010/05/01English200
Guidance on Good Cell Culture Practice2005/06/01English178
The Use of Fetal Bovine Serum: Ethical or Scientific Problem?2002/03/01English155
A Modular Approach to the ECVAM Principles on Test Validity2004/11/01English138
In Vitro Models of the Intestinal Barrier2001/11/01English135
The Use of Reconstructed Human Epidermis for Skin Absorption Testing: Results of the Validation Study2008/05/01English135
The ECVAM International Validation Study on in Vitro Tests for Acute Skin Irritation: Report on the Validity of the EPISKIN and EpiDerm Assays and on the Skin Integrity Function Test2007/12/01English111
‘Human-on-a-chip’ Developments: A Translational Cutting-edge Alternative to Systemic Safety Assessment and Efficiency Evaluation of Substances in Laboratory Animals and Man?2012/10/01English110
Estimates for Worldwide Laboratory Animal Use in 20052008/07/01English104
The use of Fish Cells in Ecotoxicology: The Report and Recommendations of ECVAM Workshop 47,2003/05/01English102
Metabolism: A Bottleneck inIn VitroToxicological Test Development2006/02/01English100
Exposure of Bronchial Epithelial Cells to Whole Cigarette Smoke: Assessment of Cellular Responses2005/06/01English88
A Review of In Silico Tools as Alternatives to Animal Testing: Principles, Resources and Applications2020/07/01English87
A Comparative Evaluation of In Vitro Skin Sensitisation Tests: The Human Cell-line Activation Test (h-CLAT) versus the Local Lymph Node Assay (LLNA)2010/08/01English86
A Review of the Implementation of the Embryonic Stem Cell Test (EST)2009/07/01English86
Anaesthesia and Post-operative Analgesia following Experimental Surgery in Laboratory Rodents: Are we Making Progress?2005/04/01English81
Chemical Reactivity Measurement and the Predictive Identification of Skin Sensitisers2008/05/01English78
An Inter-laboratory Study to Evaluate the Effects of Medium Composition on the Differentiation and Barrier Function of Caco-2 Cell Lines2005/12/01English77
An Analysis of the Use of Animal Models in Predicting Human Toxicology and Drug Safety2014/06/01English75
The Registry of Cytotoxicity: Toxicity Testing in Cell Cultures to Predict Acute Toxicity (LD50) and to Reduce Testing in Animals2003/03/01English74
An Estimate of the Number of Animals Used for Scientific Purposes Worldwide in 20152019/11/01English71
Reducing the Use of Laboratory Animals in Biomedical Research: Problems and Possible Solutions1998/05/01English65
The Three Rs: The Way Forward1995/11/01English65
The Development of the Three Rs Concept1995/05/01English64