Expert Opinion on Drug Discovery

Titel Veröffentlichungsdatum Sprache Zitate
Organs-on-a-chip: a new tool for drug discovery2014/03/12English143
A renaissance of neural networks in drug discovery2016/07/04English143
Going further than Lipinski's rule in drug design2012/01/13English142
Polyether ionophores: broad-spectrum and promising biologically active molecules for the control of drug-resistant bacteria and parasites2009/02/01English140
Rodent models for Alzheimer’s disease drug discovery2015/04/30English139
Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders2009/06/09English136
An overview of late-stage functionalization in today’s drug discovery2019/08/14English136
Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics2019/12/17English135
Rhodanine as a scaffold in drug discovery: a critical review of its biological activities and mechanisms of target modulation2012/05/19English132
An overview of molecular fingerprint similarity search in virtual screening2015/12/04English126
Drug discovery for a new generation of covalent drugs2012/05/19English123
Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery2020/03/25English123
Advances in computational methods to predict the biological activity of compounds2010/05/22English115
Broad-spectrum coronavirus antiviral drug discovery2019/03/08English114
Animal models of chronic obstructive pulmonary disease2014/04/23English114
Stabilization of protein-protein interactions in drug discovery2017/07/11English110
Candidiasis drug discovery and development: new approaches targeting virulence for discovering and identifying new drugs2013/06/06English109
Artificial intelligence in drug discovery: recent advances and future perspectives2021/04/02English105
Fluoxetine: a case history of its discovery and preclinical development2014/04/16English104
How to design multi-target drugs2007/06/01English104
PROTACs– a game-changing technology2019/09/20English103
Challenges identifying efficacious miRNA therapeutics for cancer2020/05/18English102
Using zebrafish to assess the impact of drugs on neural development and function2009/06/09English101
Discovery and development of tramadol for the treatment of pain2017/09/17English100
Support vector machines for drug discovery2013/12/05English96
The discovery of vemurafenib for the treatment of BRAF-mutated metastatic melanoma2016/06/23English95
What is the current value of MM/PBSA and MM/GBSA methods in drug discovery?2021/06/24English95
Peptide and peptoid foldamers in medicinal chemistry2011/11/02English95
What has virtual screening ever done for drug discovery?2008/07/16English92
Animal models for acute radiation syndrome drug discovery2015/03/27English92