Titel	Veröffentlichungsdatum	Sprache	Zitate
Click Chemistry and Medicinal Chemistry: A Case of “Cyclo‐Addiction”	2008/05/08	English	167
Characterization of Solid Counterfeit Drug Samples by Desorption Electrospray Ionization and Direct‐analysis‐in‐real‐time Coupled to Time‐of‐flight Mass Spectrometry	2006/06/30	English	160
Why Hydroxamates May Not Be the Best Histone Deacetylase Inhibitors—What Some May Have Forgotten or Would Rather Forget?	2015/11/25	English	159
Malaria Chemotherapeutics Part I: History of Antimalarial Drug Development, Currently Used Therapeutics, and Drugs in Clinical Development	2007/06/27	English	158
A PEG‐Based Biocompatible Block Catiomer with High Buffering Capacity for the Construction of Polyplex Micelles Showing Efficient Gene Transfer toward Primary Cells	2006/03/29	English	158
Prediction of ADMET Properties	2006/09/01	English	157
Discovery of MK‐8742: An HCV NS5A Inhibitor with Broad Genotype Activity	2013/10/14	English	156
Covalent Inhibition in Drug Discovery	2019/03/26	English	151
Towards an Integrated Description of Hydrogen Bonding and Dehydration: Decreasing False Positives in Virtual Screening with the HYDE Scoring Function	2008/06/05	English	150
Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates	2017/03/22	English	148
The Tunable Functionality of α,β‐Unsaturated Carbonyl Compounds Enables Their Differential Application in Biological Systems	2010/02/19	English	145
Exploring Chemical Modifications for siRNA Therapeutics: A Structural and Functional Outlook	2010/02/19	English	145
Evaluation of tert‐Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities	2015/01/28	English	145
Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD+‐Dependent Histone Deacetylases (Sirtuins)	2007/09/26	English	142
Multitarget Drug Discovery and Polypharmacology	2016/04/09	English	141
Mannosylated G(0) Dendrimers with Nanomolar Affinities to Escherichia coli FimH	2007/07/31	English	140
Small‐Molecule Inhibitors of the Hedgehog Signaling Pathway as Cancer Therapeutics	2010/03/30	English	137
Central Nicotinic Receptors: Structure, Function, Ligands, and Therapeutic Potential	2007/05/31	English	137
The Lab Oddity Prevails: Discovery of Pan‐CDK Inhibitor (R)‐S‐Cyclopropyl‐S‐(4‐{[4‐{[(1R,2R)‐2‐hydroxy‐1‐methylpropyl]oxy}‐5‐(trifluoromethyl)pyrimidin‐2‐yl]amino}phenyl)sulfoximide (BAY 1000394) for the Treatment of Cancer	2013/05/13	English	134
Discovery of Riociguat (BAY 63‐2521): A Potent, Oral Stimulator of Soluble Guanylate Cyclase for the Treatment of Pulmonary Hypertension	2009/05/04	English	131
Cyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein–Protein Interactions	2015/11/13	English	131
The Tubulin Colchicine Domain: a Molecular Modeling Perspective	2011/10/12	English	130
Half‐Life Extension of Biopharmaceuticals using Chemical Methods: Alternatives to PEGylation	2016/10/24	English	130
Paclitaxel And Docetaxel Resistance: Molecular Mechanisms and Development of New Generation Taxanes	2007/06/27	English	128
Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer	2017/10/16	English	126
Discovery of Isoerianin Analogues as Promising Anticancer Agents	2011/01/14	English	125
The Trifluoroethylamine Function as Peptide Bond Replacement	2007/11/29	English	125
PET Imaging of CXCR4 Receptors in Cancer by a New Optimized Ligand	2011/07/20	English	125
Galloflavin (CAS 568‐80‐9): A Novel Inhibitor of Lactate Dehydrogenase	2011/11/04	English	124
The Emerging Therapeutic Potential of Histone Methyltransferase and Demethylase Inhibitors	2009/09/28	English	123