| APACHE II | 1985/10/01 | English | 11,267 |
| Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care | 2001/07/01 | English | 5,600 |
| American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference | 1992/06/01 | English | 3,453 |
| Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units | 1998/11/01 | English | 2,182 |
| Multiple Organ Dysfunction Score | 1995/10/01 | English | 1,620 |
| Evaluation of delirium in critically ill patients: Validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) | 2001/07/01 | English | 1,462 |
| APACHE—acute physiology and chronic health evaluation: a physiologically based classification system | 1981/08/01 | English | 1,251 |
| PRISM III | 1996/05/01 | English | 1,243 |
| Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult | 2002/01/01 | English | 1,175 |
| Nosocomial infections in medical intensive care units in the United States | 1999/05/01 | English | 945 |
| Pediatric risk of mortality (PRISM) score | 1988/11/01 | English | 916 |
| Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction | 1999/07/01 | English | 886 |
| A simplified acute physiology score for ICU patients | 1984/11/01 | English | 761 |
| Effect of a nursing-implemented sedation protocol on the duration of mechanical ventilation | 1999/12/01 | English | 648 |
| Sir Isaac Newton, sepsis, SIRS, and CARS | 1996/07/01 | English | 599 |
| Assessing pain in critically ill sedated patients by using a behavioral pain scale | 2001/12/01 | English | 596 |
| Ultrasound guidance for placement of central venous catheters | 1996/12/01 | English | 568 |
| Trauma score | 1981/09/01 | English | 567 |
| Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients | 1999/07/01 | English | 564 |
| Confirmatory interleukin-1 receptor antagonist trial in severe sepsis | 1997/07/01 | English | 557 |
| Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients* | 2002/09/01 | English | 538 |
| Early enteral nutrition in acutely ill patients: A systematic review | 2001/12/01 | English | 532 |
| Epidemiology of sepsis: An update | 2001/07/01 | English | 531 |
| Stress doses of hydrocortisone reverse hyperdynamic septic shock | 1999/04/01 | English | 530 |
| Reversal of late septic shock with supraphysiologic doses of hydrocortisone | 1998/04/01 | English | 528 |
| Acute renal failure in intensive care units--Causes, outcome, and prognostic factors of hospital mortality | 1996/02/01 | English | 528 |
| Memory, delusions, and the development of acute posttraumatic stress disorder-related symptoms after intensive care | 2001/03/01 | English | 512 |
| Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury | 2002/04/01 | English | 493 |
| Therapeutic intervention scoring system | 1974/03/01 | English | 485 |
| Half the families of intensive care unit patients experience inadequate communication with physicians | 2000/08/01 | English | 477 |