Journal of Pharmacology and Experimental Therapeutics

Titel Veröffentlichungsdatum Sprache Zitate
Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates2014/04/30English194
Mechanistic Studies on Metabolic Interactions between Gemfibrozil and Statins2002/06/01English193
Unmasking the Dynamic Interplay between Intestinal P-Glycoprotein and CYP3A42002/03/01English193
Three-Dimensional Quantitative Structure-Activity Relationship for Inhibition of Human Ether-a-Go-Go-Related Gene Potassium Channel2002/05/01English193
Antiplatelet Agents Aspirin and Clopidogrel Are Hydrolyzed by Distinct Carboxylesterases, and Clopidogrel Is Transesterificated in the Presence of Ethyl Alcohol2006/08/30English191
Pharmacological Effects of Lu AA21004: A Novel Multimodal Compound for the Treatment of Major Depressive Disorder2011/12/09English191
NF-E2-Related Factor 2 Inhibits Lipid Accumulation and Oxidative Stress in Mice Fed a High-Fat Diet2008/02/15English190
Influence of Opioid Agonists on Cardiac HumanEther-a-go-go-related Gene K+Currents2002/11/01English189
N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective Vanilloid Receptor 1 Antagonist with Analgesic Properties: II. In Vivo Characterization in Rat Models of Inflammatory and Neuropathic Pain2003/04/29English188
Human Organic Anion Transporters and Human Organic Cation Transporters Mediate Renal Antiviral Transport2002/03/01English186
σ-1 Receptors (σ1Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export2003/05/02English186
The Selective α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide Hydrochloride] Enhances GABAergic Synaptic Activity in Brain Slices and Restores Auditory Gating Deficits in Anesthetized Rats2004/11/02English185
Thiazolidinedione Class of Peroxisome Proliferator-Activated Receptor γ Agonists Prevents Neuronal Damage, Motor Dysfunction, Myelin Loss, Neuropathic Pain, and Inflammation after Spinal Cord Injury in Adult Rats2006/12/13English184
Amodiaquine Clearance and Its Metabolism toN-Desethylamodiaquine Is Mediated by CYP2C8: A New High Affinity and Turnover Enzyme-Specific Probe Substrate2002/02/01English183
Optimal Structure Requirements for Pluronic Block Copolymers in Modifying P-glycoprotein Drug Efflux Transporter Activity in Bovine Brain Microvessel Endothelial Cells2003/02/01English183
Anxiolytic-Like Effects of κ-Opioid Receptor Antagonists in Models of Unlearned and Learned Fear in Rats2007/09/06English183
Potent Mechanism-Based Inhibition of Human CYP2B6 by Clopidogrel and Ticlopidine2003/10/16English182
MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition2015/09/25English182
Metabolism of Flavonoids via Enteric Recycling: Role of Intestinal Disposition2002/12/13English182
Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death2008/12/12English182
Peroxynitrite Is a Critical Mediator of Acetaminophen Hepatotoxicity in Murine Livers: Protection by Glutathione2002/11/01English181
An Inverse Agonist Selective for α5 Subunit-Containing GABAA Receptors Enhances Cognition2005/12/02English181
Inhibition of Btk with CC-292 Provides Early Pharmacodynamic Assessment of Activity in Mice and Humans2013/05/24English179
Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain2011/04/19English179
Identification and Characterization of Cholest-4-en-3-one, Oxime (TRO19622), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis2007/05/11English179
Antitumor Activity of Sphingosine Kinase Inhibitors2006/04/21English178
Mechanism-Based Inactivation of CYP3A by HIV Protease Inhibitors2004/11/02English177
Cellular Uptake and Efflux of the Tea Flavonoid (-)Epicatechin-3-gallate in the Human Intestinal Cell Line Caco-22003/09/11English177
Functions of Galectin-3 and Its Role in Fibrotic Diseases2014/09/05English177
Prostaglandin E2 Receptor EP4 Contributes to Inflammatory Pain Hypersensitivity2006/09/11English176