Xenobiotica

Titel Veröffentlichungsdatum Sprache Zitate
Metabolism of Alkenebenzene Derivatives in the Rat I.p-Methoxyallylbenzene (Estragole) andp-Methoxypropenylbenzene (Anethole)1973/01/01English50
Pharmacokinetics and metabolism of dofetilide in mouse, rat, dog and man1992/01/01English50
Reaction of arylnitroso compounds with mercaptans1980/01/01English50
Metabolism and kinetics of amlodipine in man1988/01/01English50
Pathways involved in the metabolism and activation of polycyclic hydrocarbons1986/01/01English50
Metabolism of albendazole and albendazole sulphoxide by ruminal and intestinal fluids of sheep and cattle1992/01/01English50
Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man1999/01/01English50
Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device2014/07/28English50
Functional characterization of five CYP2C8 variants and prediction of CYP2C8 genotype-dependent effects onin vitroandin vivodrug–drug interactions2010/05/11English50
Contribution of human CYP3A subfamily members to the 6-hydroxylation of chlorzoxazone1997/01/01English50
Chemical reactivity and biological activity of chalcones and other α,β-unsaturated carbonyl compounds2013/01/23English50
Diclofenac metabolism in the mouse: Novelin vivometabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry2011/09/28English50
Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up2000/01/01English50
Purification and characterization of oxidoreductases-catalyzing carbonyl reduction of the tobacco-specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human liver cytosol2000/01/01English50
Catalytic activities, protein- and mRNA-expression of cytochrome P450 isoenzymes in intestinal cell lines1998/01/01English50
In vitro and in vivo pharmacokinetic characterization of mavacamten, a first-in-class small molecule allosteric modulator of beta cardiac myosin2018/10/01English49
In vitrometabolism of gefitinib in human liver microsomes2004/01/01English49
The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes2011/04/09English49
Drug Hydroxylation and Glucuronidation in Liver Microsomes of Phenobarbital-Treated Rats1973/01/01English49
Absorption, Excretion and Metabolism of a New Dihydropyridine Diester Cerebral Vasodilator in Rats and Dogs1977/01/01English49
Biotransformation of the fungicides hexachlorobenzene and pentachloronitrobenzene1981/01/01English49
Absorption, elimination and metabolism of trichloroethylene: a quantitative comparison between rats and mice1986/01/01English49
Modification of hepatic drug-metabolizing enzymes in rat fed naturally occurring allyl sulphides1994/01/01English49
Induction of drug-metabolizing enzymes by xenobiotics1990/01/01English49
Different expression of hepatic and renal cytochrome P450s between the streptozotocininduced diabetic mouse and rat2001/01/01English49
Metabolic Activation of Haloalkanes and Testsin vitrofor Mutagenicity1977/01/01English48
Characterization of the inhibition of P4501A2 by furafylline1994/01/01English48
Generation of proliferating human hepatocytes using upcyte®technology: characterisation and applications in induction and cytotoxicity assays2012/04/24English48
Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3 and 51998/01/01English48
Pharmacokinetics of the novel, high-affinity and selective dopamine D3 receptor antagonist SB-277011 in rat, dog and monkey:in vitro/in vivocorrelation and the role of aldehyde oxidase2001/01/01English48