Titel	Veröffentlichungsdatum	Sprache	Zitate
Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol	2006/02/27	English	63
Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue	2009/01/07	English	61
MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages	2010/04/12	English	60
NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity	2010/02/22	English	59
Chemical-genetic profile analysis of five inhibitory compounds in yeast	2010/08/06	English	44
Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II	2008/08/01	English	41
Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives	2012/10/03	English	38
Electronic properties of amino acid side chains: quantum mechanics calculation of substituent effects	2005/08/03	English	38
The Terebridae and teretoxins: Combining phylogeny and anatomy for concerted discovery of bioactive compounds	2010/09/17	English	36
Chemogenetic fingerprinting by analysis of cellular growth dynamics	2008/08/22	English	35
DG-AMMOS: A New tool to generate 3D conformation of small molecules using D istance G eometry and A utomated M olecular M echanics O ptimization for in silico S creening	2009/11/13	English	32
Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus	2009/01/16	English	29
Chemical tools selectively target components of the PKA system	2009/02/12	English	28
Dietary phenethylisothiocyanate attenuates bowel inflammation in mice	2010/04/27	English	21
Glycosylated VCAM-1 isoforms revealed in 2D western blots of HUVECs treated with tumoral soluble factors of breast cancer cells	2009/11/22	English	19
Development of ERK Activity Sensor, an in vitro, FRET-based sensor of Extracellular Regulated Kinase activity	2005/07/05	English	19
Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator	2006/02/08	English	16
HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck	2012/03/15	English	15
High toxicity and specificity of the saponin 3-GlcA-28-AraRhaxyl-medicagenate, from Medicago truncatula seeds, for Sitophilus oryzae	2012/07/02	English	15
The effect of amino acid deletions and substitutions in the longest loop of GFP	2007/06/26	English	14
Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae	2008/01/07	English	14
Identification Of Small Molecule TRABID Deubiquitinase Inhibitors By Computation-Based Virtual Screen	2012/05/14	English	13
Enhancement of intracellular γ-tocopherol levels in cytokine-stimulated C3H 10T1/2 fibroblasts: relation to NO synthesis, isoprostane formation, and tocopherol oxidation	2007/07/03	English	12
Bioinformatic analysis of xenobiotic reactive metabolite target proteins and their interacting partners	2009/06/12	English	12
Mitotic slippage in non-cancer cells induced by a microtubule disruptor, disorazole C1	2010/02/11	English	6
Local and global modes of drug action in biochemical networks	2009/04/07	English	6
Comprehensive predictions of target proteins based on protein-chemical interaction using virtual screening and experimental verifications	2012/04/05	English	6
Covalent attachment of the plant natural product naringenin to small glass and ceramic beads	2005/10/10	English	4
Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: A new use of a known compound	2011/05/31	English	4
Development of an HPLC method for determination of pentachloronitrobenzene, hexachlorobenzene and their possible metabolites	2011/11/23	English	3