Hereditary Cancer in Clinical Practice

Title Publication Date Language Citations
Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patients2010/06/17English97
The role of BRCA1 and BRCA2 mutations in prostate, pancreatic and stomach cancers2015/08/01English87
Germline deletions in the EPCAM gene as a cause of Lynch syndrome – literature review2013/08/12English76
Familial Adenomatous Polyposis: Experience from a Study of 1164 Unrelated German Polyposis Patients2005/09/15English70
Syndromic gastrointestinal stromal tumors2016/07/19English62
Colorectal carcinoma in the course of inflammatory bowel diseases2019/07/12English53
Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management2009/12/01English48
Factors Influencing Cancer Risk Perception in High Risk Populations: A Systematic Review2011/05/19English48
The effect of neoadjuvant platinum-based chemotherapy in BRCA mutated triple negative breast cancers -systematic review and meta-analysis2019/03/25English44
The genetic basis of colonic adenomatous polyposis syndromes2017/03/16English43
Hereditary breast cancer: ever more pieces to the polygenic puzzle2013/09/11English40
Intensive breast screening in BRCA2 mutation carriers is associated with reduced breast cancer specific and all cause mortality2016/04/14English39
Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report2017/10/10English39
Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report2019/02/28English36
Prevalance of BRCA1 and BRCA2 mutations in familial breast cancer patients in Lebanon2012/06/19English34
The Prospective Lynch Syndrome Database reports enable evidence-based personal precision health care2020/03/14English34
PARP inhibitors2015/01/17English34
CDKN2A germline alterations and the relevance of genotype-phenotype associations in cancer predisposition2021/03/25English33
Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario2009/08/23English33
Familial adenomatous polyposis of the colon2013/10/22English31
Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Medellín, Colombia2014/04/17English31
Cytotoxic and targeted therapy for hereditary cancers2016/08/23English31
Drug therapy for hereditary cancers2011/08/06English30
High frequency of BRCA1, but not CHEK2 or NBS1 (NBN), founder mutations in Russian ovarian cancer patients2009/02/25English29
Plasma homocysteine levels and genetic polymorphisms in folate metablism are associated with breast cancer risk in chinese women2014/02/21English29
BRAF mutations in thyroid tumors from an ethnically diverse group2012/08/27English29
Familial gastric cancer: detection of a hereditary cause helps to understand its etiology2012/12/01English28
Prevalence and predictors of germline CDKN2A mutations for melanoma cases from Australia, Spain and the United Kingdom2014/11/20English28
Lynch syndrome: barriers to and facilitators of screening and disease management2011/09/07English27
The contribution of CHEK2 to the TP53-negative Li-Fraumeni phenotype2009/02/17English26