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Drug Metabolism and Pharmacokinetics
Title
Publication Date
Language
Citations
Xenobiotic-Metabolizing Enzymes Involved in Activation and Detoxification of Carcinogenic Polycyclic Aromatic Hydrocarbons
2006/01/01
English
424
Mechanistic Basis of Using Body Size and Maturation to Predict Clearance in Humans
2009/01/01
English
372
Albumin as Fatty Acid Transporter
2009/01/01
English
309
Organ/body-on-a-chip based on microfluidic technology for drug discovery
2018/02/01
English
279
Tissue-specific mRNA Expression Profiles of Human ATP-binding Cassette and Solute Carrier Transporter Superfamilies
2005/01/01
English
275
Human Carboxylesterase Isozymes: Catalytic Properties and Rational Drug Design
2006/01/01
English
271
Metformin is a Superior Substrate for Renal Organic Cation Transporter OCT2 rather than Hepatic OCT1
2005/01/01
English
269
A Framework for Assessing Inter-individual Variability in Pharmacokinetics Using Virtual Human Populations and Integrating General Knowledge of Physical Chemistry, Biology, Anatomy, Physiology and Genetics: A Tale of ‘Bottom-Up’ vs ‘Top-Down’ Recognition of Covariates
2009/01/01
English
263
Lessons from the Crystallographic Analysis of Small Molecule Binding to Human Serum Albumin
2009/01/01
English
229
Influence of CYP2C19 Pharmacogenetic Polymorphism on Proton Pump Inhibitor-based Therapies
2005/01/01
English
195
Metabolism of Tacrolimus (FK506) and Recent Topics in Clinical Pharmacokinetics
2007/01/01
English
187
Tissue-Specific mRNA Expression Profiles of Human Phase I Metabolizing Enzymes Except for Cytochrome P450 and Phase II Metabolizing Enzymes
2006/01/01
English
172
Molecular Aspects of Renal Handling of Aminoglycosides and Strategies for Preventing the Nephrotoxicity
2004/01/01
English
170
A comprehensive review of UDP-glucuronosyltransferase and esterases for drug development
2015/02/01
English
170
A Molecular Functional Study on the Interactions of Drugs with Plasma Proteins
2005/01/01
English
170
Drug-Metabolizing Ability of Molybdenum Hydroxylases
2006/01/01
English
156
Nuclear Receptor-Mediated Transcriptional Regulation in Phase I, II, and III Xenobiotic Metabolizing Systems
2006/01/01
English
154
Solubility and Dissolution Profile Assessment in Drug Discovery
2007/01/01
English
146
Regulation of Hepatocyte Nuclear Factor 4α-mediated Transcription
2008/01/01
English
146
Tissue-specific mRNA Expression Profiles of Human Nuclear Receptor Subfamilies
2004/01/01
English
144
In vitro-in vivo Extrapolation of Transporter-mediated Clearance in the Liver and Kidney
2009/01/01
English
143
Receptor Occupancy-based Analysis of the Contributions of Various Receptors to Antipsychotics-induced Weight Gain and Diabetes Mellitus
2005/01/01
English
134
Tissue-specific mRNA Expression Profiles of Human Solute Carrier Transporter Superfamilies
2008/01/01
English
134
The Organic Anion Transporter (OATP) Family
2004/01/01
English
132
Ethnic Differences in Genetic Polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1
2004/01/01
English
118
Multiplicity of Mammalian Reductases for Xenobiotic Carbonyl Compounds
2006/01/01
English
117
In Silico Approaches for Predicting ADME Properties of Drugs
2004/01/01
English
117
Cancer Prevention by Natural Compounds
2004/01/01
English
111
Difference in the lipid nanoparticle technology employed in three approved siRNA (Patisiran) and mRNA (COVID-19 vaccine) drugs
2021/12/01
English
107
Role of Human Hepatocyte Nuclear Factor 4α in the Expression of Drug-Metabolizing Enzymes and Transporters in Human Hepatocytes Assessed by Use of Small Interfering RNA
2007/01/01
English
107
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