European Journal of Medicinal Chemistry

Title Publication Date Language Citations
Design, synthesis, and biological evaluation of some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide hybrids as MTDLs for Alzheimer's disease therapy2024/05/01English
Development of benzimidazole-based compounds as novel capsid assembly modulators for the treatment of HBV infection2024/05/01English
Structure optimizing of flavonoids against both MRSA and VRE2024/05/01English
Discovery of novel diaryl substituted isoquinolin-1(2H)-one derivatives as hypoxia-inducible factor-1 signaling inhibitors for the treatment of rheumatoid arthritis2024/05/01English
Discovery of the small molecular inhibitors against sclerostin loop3 as potential anti-osteoporosis agents by structural based virtual screening and molecular design2024/05/01English
Design, synthesis, and biological evaluation of novel benzimidazole derivatives as anti-cervical cancer agents through PI3K/Akt/mTOR pathway and tubulin inhibition2024/05/01English
Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation2024/05/01English
New pyridazinone derivatives as inhibitors of platelet aggregation1995/01/01English
Inhibitors of 5-lipoxygenase: a therapeutic potential yet to be fully realized?1999/09/01
Naphthazarin derivatives (IV): synthesis, inhibition of DNA topoisomerase I and cytotoxicity of 2- or 6-acyl-5,8-dimethoxy-1,4-naphthoquinones2000/03/01English
Total synthesis and structural modification of the dibenzylbutane lignan LCA as a potent anti-inflammatory agent against LPS-induced acute lung injury2024/03/01English
Targeting bromodomian-containing protein 8 (BRD8): An advanced tool to interrogate BRD82024/03/01English
Discovery of N-(5-amido-2-methylphenyl)-5-methylisoxazole-3-carboxamide as dual CSF-1R/c-Kit Inhibitors with improved stability and BBB permeability2024/03/01English
Discovery of potent small molecule inhibitors of histone lysine methyltransferase NSDs2024/03/01English
The COREPA approach to lead generation: an application to ACE-inhibitors1999/09/01
The low affinity PCP sites in the rat cerebellum not only bind TCP-like but also BTCP-like structures2000/03/01
Synthesis and pharmacological evaluation of new4-[2-(7-heterocyclemethoxynaftalen-2-ylmethoxy)ethyl]benzoic acidsas LTD4-antagonists2000/04/01
New 2-sulfonamidothiazoles substituted at C-4: synthesis of polyoxygenated aryl derivatives and in vitro evaluation of antifungal activity1999/09/01
Inhibition of Son of Sevenless Homologue 1 (SOS1): Promising therapeutic treatment for KRAS-mutant cancers2023/12/01English
Synthesis, cytotoxic activity evaluation and mechanistic investigation of novel 3,7-diarylsubstituted 6-azaindoles2023/12/01English
Graphical abstract TOC2023/11/01English
Synthesis and evaluation of aromatic BDSF bioisosteres on biofilm formation and colistin sensitivity in pathogenic bacteria2023/12/01English
Kinetic modelling of the P-glycoprotein mediated efflux with a large-scale matched molecular pair analysis2023/12/01English
Targeting autophagy with small-molecule activators for potential therapeutic purposes2023/11/01English
Novel ProTide prodrugs of 5-fluoro-2′-deoxyuridine for the treatment of liver cancer2023/11/01English
Anti-influenza virus activities and mechanism of antrafenine analogs2023/11/01English
Emerging opportunities to treat idiopathic pulmonary fibrosis: Design, discovery, and optimizations of small-molecule drugs targeting fibrogenic pathways2023/11/01English
Synthesis of cannabidiol-based compounds as ACE2 inhibitors with potential application in the treatment of COVID-192023/11/01English
Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase2023/11/01English
Discovery of N-(2-oxoethyl) sulfanilamide-derived inhibitors of KAT6A (MOZ) against leukemia by an isostere strategy2023/11/01English