Anti-Cancer Drugs

Title Publication Date Language Citations
Selective cytostatic and cytotoxic effects of glucosinolates hydrolysis products on human colon cancer cells in viro1998/02/01English77
Demethylation by 5-aza-2??-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor ?? gene in human colon carcinoma cells1998/10/01English76
Antiproliferative effect of quercetin in the human U138MG glioma cell line2006/07/01English76
Protein kinase C: a worthwhile target for anticancer drugs?1997/01/01English75
Inhibition of human ovarian cancer cell proliferation in vitro by ginsenoside Rh2 and adjuvant effects to cisplatin in vivo1991/02/01English74
Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway2006/06/01English74
Induction of apoptosis by gallic acid in lung cancer cells1999/10/01English74
DNA topoisomerase targeting drugs: mechanisms of action and perspectives1997/10/01English73
Bisphosphonates inhibit stromelysin-1 (MMP-3), matrix metalloelastase (MMP-12), collagenase-3 (MMP-13) and enamelysin (MMP-20), but not urokinase-type plasminogen activator, and diminish invasion and migration of human malignant and endothelial cell lines2002/03/01English73
Pharmacokinetics of doxorubicin administered i.v. as Myocet (TLC D-99; liposome-encapsulated doxorubicin citrate) compared with conventional doxorubicin when given in combination with cyclophosphamide in patients with metastatic breast cancer2003/03/01English72
A phase I clinical and pharmacological study of oral 9-nitrocamptothecin, a novel water-insoluble topoisomerase I inhibitor1998/01/01English72
Antitumor activity of sodium valproate in cultures of human neuroblastoma cells1996/09/01English71
Antitumor immunity induced by photodynamic therapy with aluminum disulfonated phthalocyanines and laser light1994/08/01English71
Structure-activity studies on gossypol in tumor cell lines2000/03/01English71
AnvirzelTM, an extract of Nerium oleander, induces cell death in human but not murine cancer cells2000/07/01English70
Phase II trial of gemcitabine as prolonged infusion in metastatic breast cancer1999/08/01English70
Efficacy and safety of Herceptin® in women with metastatic breast cancer: results from pivotal clinical studies2001/12/01English69
Phase II study of paclitaxel in pretreated advanced gastric cancer1998/04/01English67
A phase I clinical and pharmacokinetic study of the topoisomerase I inhibitor topotecan (SK&F 104864) given as an intravenous bolus every 21 days1992/08/01English67
Experimental antitumor activity and pharmacokinetics of the camptothecin analog irinotecan (CPT-11) in mice1996/06/01English66
Improved anti-tumor response rate with decreased cardiotoxicity of non-pegylated liposomal doxorubicin compared with conventional doxorubicin in first-line treatment of metastatic breast cancer in patients who had received prior adjuvant doxorubicin: results of a retrospective analysis2006/06/01English66
Pharmacokinetic advantage of intra-arterial hepatic oxaliplatin administration: comparative results with cisplatin using a rabbit VX2 tumor model2004/07/01English66
Sustained complete remission of metastatic dermatofibrosarcoma protuberans with imatinib mesylate2005/04/01English65
Apoptosis in murine tumors treated with chemotherapy agents1995/06/01English65
Inhibitors of cancer cell multidrug resistance mediated by breast cancer resistance protein (BCRP/ABCG2)2006/03/01English65
Ras biochemistry and farnesyl transferase inhibitors: a literature survey2001/03/01English64
17-(Allylamino)-17-demethoxygeldanamycin activity in human melanoma models2004/04/01English63
Inhibition of angiogenesis by non-toxic doses of temozolomide2003/08/01English62
Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein1999/09/01English62
Tamoxifen and epigallocatechin gallate are synergistically cytotoxic to MDA-MB-231 human breast cancer cells2004/10/01English62