Frontiers in Drug Discovery

Title Publication Date Language Citations
Grand Challenges of Computer-Aided Drug Design: The Road Ahead2021/07/2821
Is Covid-19 Severity Associated With ACE2 Degradation?2022/01/2519
Addressing Antibiotic Failure—Beyond Genetically Encoded Antimicrobial Resistance2022/05/309
Deep Machine Learning for Computer-Aided Drug Design2022/02/078
Deep Learning Prediction of Adverse Drug Reactions in Drug Discovery Using Open TG–GATEs and FAERS Databases2021/10/278
Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism2022/01/147
Harnessing the Potential of Human Pluripotent Stem Cell-Derived Motor Neurons for Drug Discovery in Amyotrophic Lateral Sclerosis: From the Clinic to the Laboratory and Back to the Patient2021/11/117
The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-192022/03/307
Post-Pandemic Drug Discovery and Development: Facing Present and Future Challenges2021/07/287
Nanobodies: COVID-19 and Future Perspectives2022/07/186
Furin and COVID-19: Structure, Function and Chemoinformatic Analysis of Representative Active Site Inhibitors2022/05/106
Peptide-Based Strategies Against SARS-CoV-2 Attack: An Updated In Silico Perspective2022/05/106
Drug discovery and development: introduction to the general public and patient groups2023/05/246
Developing Small-Molecule Inhibitors of Protein-Protein Interactions Involved in Viral Entry as Potential Antivirals for COVID-192022/04/255
Current advances in our understanding of circular RNA (circRNA) in Alzheimer’s disease (AD); the potential utilization of synthetic circRNAs as a therapeutic strategy in the clinical management of AD2022/08/245
The grand challenge of discovering new cardiovascular drugs2022/09/234
Integrating diverse layers of omic data to identify novel drug targets in Listeria monocytogenes2022/09/234
A machine learning-based virtual screening for natural compounds capable of inhibiting the HIV-1 integrase2022/10/213
Nine receptors and binding proteins, four drugs, and one woman: Historical and personal perspectives2022/10/213
The Prospects of Monte Carlo Antibody Loop Modelling on a Fault-Tolerant Quantum Computer2022/07/083
The critical role of mode of action studies in kinetoplastid drug discovery2023/05/103
Zingiber officinale (Ginger) as a treatment for inflammatory bowel disease: A review of current literature2022/12/083
Review of Clinical Trials of COVID-19 Vaccination Booster in SARS-CoV-2 Variants Era: To Take It or Not To Take It2022/03/223
Overcoming Market Failures in Pandemic Drug Discovery Through Open Science: A Canadian Solution2022/05/263
Discovery of novel spike/ACE2 inhibitory macrocycles using in silico reinforcement learning2022/12/232
Coumarin-1,2,3-triazole hybrids as leading-edge anticancer agents2022/12/062
Oxidized phospholipids are biomarkers, drug targets, and drug leads2022/11/032
Artificial intelligence for antiviral drug discovery in low resourced settings: A perspective2022/11/022
From drugs to targets: Reverse engineering the virtual screening process on a proteomic scale2022/10/202
In silico identification of potential inhibitors of acyl carrier protein reductase and acetyl CoA carboxylase of Plasmodium falciparum in antimalarial therapy2023/01/202