Drug Design, Development and Therapy

Title Publication Date Language Citations
Animal models of ischemic stroke and their application in clinical research2015/07/01English22
ACAM2000™: The new smallpox vaccine for United States Strategic National Stockpile2010/05/01English15
Metal complexes in cancer therapy – an update from drug design perspective2017/03/01English14
Current development of biodegradable polymeric materials for biomedical applications2018/09/01English14
Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway2015/08/01English10
An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides2014/12/01English10
Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery2016/01/01English10
<p>A Network Pharmacology-Based Strategy For Predicting Active Ingredients And Potential Targets Of LiuWei DiHuang Pill In Treating Type 2 Diabetes Mellitus</p>2019/11/01English10
<p>Systematic elucidation of the mechanism of geraniol via network pharmacology</p>2019/04/01English9
8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications2013/10/01English9
<p>Salvianolic acid A attenuates CCl<sub>4</sub>-induced liver fibrosis by regulating the PI3K/AKT/mTOR, Bcl-2/Bax and caspase-3/cleaved caspase-3 signaling pathways</p>2019/05/01English8
Combination of Ginsenoside Rg1 and Astragaloside IV reduces oxidative stress and inhibits TGF-&beta;1/Smads signaling cascade on renal fibrosis in rats with diabetic nephropathy2018/10/01English8
Molecular mechanisms of cisplatin resistance in cervical cancer2016/06/01English8
Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties2014/10/01English8
Studies of selective TNF inhibitors in the treatment of brain injury from stroke and trauma: a review of the evidence to date2014/11/01English8
Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer&#39;s disease and Parkinson&#39;s disease2017/03/01English8
Submucosal injection solution for gastrointestinal tract endoscopic mucosal resection and endoscopic submucosal dissection2008/08/01English7
<p>The Osteoprotective Effects Of Kaempferol: The Evidence From In Vivo And In Vitro Studies</p>2019/10/01English7
<p>Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages</p>2020/08/01English7
Resistance to anti-VEGF therapy in neovascular age-related macular degeneration: a comprehensive review2016/06/01English7
Metformin: a review of its potential indications2017/08/01English7
Modulation of neurotrophic signaling pathways by&nbsp;polyphenols2015/12/01English7
<p>Paclitaxel alleviated sepsis-induced acute lung injury by activating MUC1 and suppressing TLR-4/NF-κB pathway</p>2019/09/01English7
Linezolid: a review of its properties, function, and use in critical care2018/06/01English7
<p>Ruthenium Complexes as Anticancer Agents: A Brief History and Perspectives</p>2020/12/01English7
Leishmaniasis in humans: drug or vaccine therapy?2017/12/01English6
Drugs in development for toxoplasmosis: advances, challenges, and current status2017/01/01English6
Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells2016/08/01English6
<p>Comparison of dexmedetomidine and sufentanil as adjuvants to local anesthetic for epidural labor analgesia: a randomized controlled trial</p>2019/04/01English6
<p>Formulation and evaluation of simvastatin polymeric nanoparticles loaded in hydrogel for optimum wound healing purpose</p>2019/05/01English6