Immunobiology

Title Publication Date Language Citations
229 Effects of combined complement complement and CD14 inhibition on Escherichia coli-induced thromboinflammation in human whole blood in the presence and absence of antibiotics2023/09/01English
235 Crystallographic and SAXS structure of the immune evasive factor GAPDH from Leptospira interrogans and interaction with human C5a2023/09/01English
118 Atypical haemolytic uraemic syndrome in the era of complement inhibiting therapy: The UK national cohort experience2023/09/01English
145 C1q dependent synaptic pruning in sepsis-associated encephalopathy (SAE)2023/09/01English
195 Measurements of complement regulators in peritoneal dialysis patients2023/09/01English
4 Controlling the membrane attack complex2023/09/01English
173 Roles of complement dysregulation and membrane attack complex formation in developmental synapse loss2023/09/01English
88 Identification and characterization of a novel complement factor I-binding protein in Pasteurella multocida2023/09/01English
120 Differential complement activation in the blood of individuals at clinical high risk for psychosis compared with healthy controls2023/09/01English
101 CD59 isoforms IRIS-1 and IRIS-2 are expressed in human and mouse brains, required for neurotransmitter release, and have a decreased expression in Alzheimer[StQuote]s disease patient[StQuote]s brains2023/09/01English
103 C3d-Directed Factor H Delivers Potent and Durable Local Complement Inhibition, Disease-Modifying Efficacy, and Decreased Renal-Derived C5b-9 Without Inhibiting Systemic Complement2023/09/01English
163 Single cell sorting and cloning of human anti-C1q autoantibodies reveals specificity for solid-phase C1q and capacity to engage Fc receptors2023/09/01English
228 The multi-faceted role of complement C3aR in the development and treatment of colorectal cancer2023/09/01English
106 Lack of MASP-1 results in delayed onset of albuminuria and prolonged survival in lupus-prone MRL/lpr mice2023/09/01English
174 Factor H-related dimer equilibrium and kinetics revealed through novel specific ELISAs2023/09/01English
144 FH desialylation as an acquired cause of Complement dysregulation in atypical Haemolytic Uraemic Syndrome2023/09/01English
212 Determinants resulting in high residual C5 activity in presence of Eculizumab or Coversin2023/09/01English
213 Complement C3 deficiency enhances the effector function of CD8+ T cells and inhibits tumour growth2023/09/01English
16 Characterization and development of CSL040, a soluble truncated fragment of complement receptor 12023/09/01English
116 Differential complement iC3b levels in baseline plasma of individuals at clinical high risk for psychosis2023/09/01English
211 Platelet supernatants modulate the inflammatory response in thrombocytopenic blood ex vivo2023/09/01English
24 The C5a/C5aR1 axis controls the induction of Germinal Center B cells, their IgM/IgG1 production and plasma cell differentiation2023/09/01English
18 A phase 2, open-label study evaluating the safety and efficacy of combination pozelimab and cemdisiran therapy in patients with paroxysmal nocturnal hemoglobinuria who switch from eculizumab2023/09/01English
35 Deciphering complement system-dependent cellular pathways in human rheumatoid arthritis synovial tissues using large single-cell computational omics2023/09/01English
125 Elevated expression of complement factor I in lung cancer cells associates with shorter survival – Potentially via non-canonical mechanism2023/09/01English
5 Synovial complement activation and imbalance after anterior cruciate ligament injury or meniscus tear as a risk factor in the development of post-traumatic osteoarthritis2023/09/01English
89 Bi-functional C5 antibody-fusion protein (LP-005) with potential best-in-class bioactivity for complement inhibition2023/09/01English
139 Antibodies targeting human complement receptor C3aR2023/09/01English
100 LPS O1-antigen-mediated complement-resistance of Klebsiella pneumoniae clinical isolates2023/09/01English
110 Investigating the Role of Complement in Cognitive Decline after Repetitive Mild Closed Head Brain Injury2023/09/01English