Science Translational Medicine

Title Publication Date Language Citations
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β2012/08/15English2,950
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies2014/02/19English2,936
Hidden Killers: Human Fungal Infections2012/12/19English2,725
Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors2011/03/23English2,303
The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice2009/11/11English1,977
Wound repair and regeneration: Mechanisms, signaling, and translation2014/12/03English1,892
Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia2014/02/19English1,759
T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia2011/08/10English1,692
PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations2016/03/02English1,600
Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape2012/03/28English1,501
CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia2013/03/20English1,440
The gut microbiota influences blood-brain barrier permeability in mice2014/11/19English1,396
Up-Regulation of PD-L1, IDO, and T regs in the Melanoma Tumor Microenvironment Is Driven by CD8 + T Cells2013/08/28English1,212
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia2015/09/02English1,209
The Placenta Harbors a Unique Microbiome2014/05/21English1,151
Early infancy microbial and metabolic alterations affect risk of childhood asthma2015/09/30English1,078
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses2017/06/28English1,050
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma2017/07/19English962
Temporal Dynamics of the Human Vaginal Microbiota2012/05/02English931
Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1- 13 C]Pyruvate2013/08/14English925
Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer2016/07/06English900
Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA–Peptide Complexes in Systemic Lupus Erythematosus2011/03/09English879
Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers2012/02/08English871
Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA2012/05/30English864
NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis2013/03/27English861
A soft, wearable microfluidic device for the capture, storage, and colorimetric sensing of sweat2016/11/23English847
Antibiotics, birth mode, and diet shape microbiome maturation during early life2016/06/15English846
Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus2011/03/09English837
Alzheimer’s Disease: The Challenge of the Second Century2011/04/06English830
Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile2012/04/04English804