Title	Publication Date	Language	Citations
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients	2004/08/01	English	1,273
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma	2012/10/01	English	1,272
AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients	2007/01/01	English	1,239
Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis	2016/12/01	English	1,231
Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis	2011/11/01	English	1,227
YAP/TAZ at the Roots of Cancer	2016/06/01	English	1,207
Smoldering and polarized inflammation in the initiation and promotion of malignant disease	2005/03/01	English	1,197
A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer	2007/10/01	English	1,141
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors	2005/10/01	English	1,132
A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma	2014/05/01	English	1,131
Identification of Distinct Basal and Luminal Subtypes of Muscle-Invasive Bladder Cancer with Different Sensitivities to Frontline Chemotherapy	2014/02/01	English	1,118
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance	2006/06/01	English	1,117
Oxidative Stress in Cancer	2020/08/01	English	1,109
Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis	2014/11/01	English	1,101
Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma	2017/08/01	English	1,100
A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth	2007/01/01	English	1,092
Nuclear factor-κB	2004/09/01	English	1,090
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner	2010/02/01	English	1,061
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl	2005/02/01	English	1,055
Mutant p53 in Cancer: New Functions and Therapeutic Opportunities	2014/03/01	English	1,045
Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents	2015/12/01	English	1,036
Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia	2014/11/01	English	1,031
Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis	2014/04/01	English	1,014
Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment	2017/07/01	English	1,004
The Microenvironmental Landscape of Brain Tumors	2017/03/01	English	994
FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase	2017/01/01	English	994
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming	2012/07/01	English	990
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized	2006/11/01	English	978
Macrophages and Therapeutic Resistance in Cancer	2015/04/01	English	976
Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer	2018/03/01	English	941