Oncogene

Title Publication Date Language Citations
DNA methylation in cancer: too much, but also too little2002/08/05English1,002
The role of cyclooxygenases in inflammation, cancer, and development1999/12/20English999
Autophagy as a cell death and tumor suppressor mechanism2004/04/12English997
Glycolysis inhibition for anticancer treatment2006/08/07English997
Perturbations of the AKT signaling pathway in human cancer2005/11/14English984
5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy2002/08/05English974
Circular RNAs in cancer: opportunities and challenges in the field2017/10/09English941
FOXO transcription factors at the interface between longevity and tumor suppression2005/11/14English940
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer2009/11/02English920
The EGF receptor family as targets for cancer therapy2000/12/27English920
Control of apoptosis by Rel/NF-κB transcription factors1999/11/22English910
The role of STATs in transcriptional control and their impact on cellular function2000/05/25English907
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression2004/04/19English897
Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors2000/05/25English890
The role of glutathione-S-transferase in anti-cancer drug resistance2003/10/20English885
The FoxO code2008/04/07English875
PI3K/Akt and apoptosis: size matters2003/12/08English873
Cell death by mitotic catastrophe: a molecular definition2004/04/12English871
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis2002/03/21English865
Epithelial–mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways2005/11/14English863
NF-κB and the immune response2006/10/30English859
How NF-κB is activated: the role of the IκB kinase (IKK) complex1999/11/22English845
Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis2008/10/27English827
Aberrant rel/nfkb genes and activity in human cancer1999/11/22English827
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues2005/12/05English822
MYC oncogenes and human neoplastic disease1999/05/13English805
CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future2002/08/05English804
Immunogenic death of colon cancer cells treated with oxaliplatin2009/11/02English799
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition2007/05/14English797
A decade of caspases2003/11/24English785