Are there sex-related differences in outcomes following thoracic aortic surgery? This study examines sex-related disparities in patients undergoing thoracic aortic aneurysm (TAA) surgery, providing insights into potential factors influencing survival rates and emphasizing the need for personalized treatment strategies. The research enrolled 455 cases undergoing TAA surgery between 2009 and 2015 in a Chinese hospital, evaluating primary outcomes and related risk factors. Results showed that females had greater indexed aortic diameters and higher aortic transvalvular pressure differences, while males had a higher rate of root involvement. Women experienced significantly increased overall mortality. These findings highlight the need for tailored surgical strategies and gender-specific guidelines in treating female patients following TAA surgery. Maximum indexed aortic diameter and cross-clamp time were key risk factors associated with females’ survival, emphasizing the importance of considering these factors in surgical planning and postoperative care.
This study aligns with Journal of Cardiothoracic Surgery's mission to advance surgical outcomes and knowledge. By identifying sex-related differences in TAA surgery, the research provides essential insights for optimizing surgical approaches and improving patient care, which directly contributes to the journal's commitment to excellence in cardiothoracic surgery.