Can understanding the neuroimmune system lead to new cardiovascular treatments? This review explores the emerging field of neuroimmunology in cardiovascular disease (CVD), highlighting the brain's role in CVD pathology. Despite medical advancements, CVD remains a leading cause of death worldwide, prompting investigation into novel therapeutic approaches. The brain contains neuroimmune niches comprising glia and immune cells, and their activation appears to modulate CVD progression in conditions such as hypertension and heart failure. This activation leads to end-organ damage. The review suggests that further research is needed to understand the long-term effects of neuroimmune activation on brain function. New research should provide a foundation for innovative therapies aimed at reducing the global impact of CVD.
As Current Hypertension Reports focuses on new findings in hypertension and related cardiovascular conditions, this review on neuroimmune mechanisms in CVD is highly relevant. The article aligns with the journal's aim by offering a concise overview of new and pertinent findings related to the neuroimmune system's role in CVD progression, potentially informing future diagnostic and therapeutic strategies.