What are the most effective methods for removing DNA contamination in forensic labs? This study investigates the cleaning protocols used in forensic genetic laboratories to prevent cross-sample contamination. Ten laboratories shared their cleaning protocols, and the efficiency of various cleaning reagents was tested and compared. The results showed that freshly made household bleach and Virkon® effectively removed all amplifiable DNA from surfaces. In contrast, DNA AWAY™ and the disinfection reagents ethanol, isopropanol, and ChemGene HLD4L did not completely remove DNA contamination. This research highlights the importance of using appropriate cleaning protocols in forensic genetic laboratories to ensure the accuracy and reliability of DNA analysis. The findings provide valuable guidance for selecting effective cleaning reagents and optimizing cleaning procedures to minimize the risk of cross-sample contamination.
Published in the International Journal of Legal Medicine, this study aligns with the journal's focus on forensic science and the application of scientific methods in legal contexts. By evaluating the effectiveness of different cleaning protocols for DNA removal, the research contributes to ensuring the reliability and validity of forensic genetic analysis.